SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000204086 RPA4 H. sapiens SSL Slorth 0.821238 View
ENSG00000096717 SIRT1 ENSG00000154016 GRAP H. sapiens SSL Slorth 0.820822 View
ENSG00000096717 SIRT1 ENSG00000125354 SEPT6 H. sapiens SSL Slorth 0.820753 View
ENSG00000076604 TRAF4 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.820565 View
ENSG00000096717 SIRT1 ENSG00000184557 SOCS3 H. sapiens SSL Slorth 0.820328 View
ENSG00000096717 SIRT1 ENSG00000107643 MAPK8 H. sapiens SSL Slorth 0.820223 View
ENSG00000096717 SIRT1 ENSG00000108469 RECQL5 H. sapiens SSL Slorth 0.820174 View
ENSG00000096717 SIRT1 ENSG00000189056 RELN H. sapiens SSL Slorth 0.820144 View
ENSG00000096717 SIRT1 ENSG00000115091 ACTR3 H. sapiens SSL Slorth 0.820048 View
ENSG00000096717 SIRT1 ENSG00000213066 FGFR1OP H. sapiens SSL Slorth 0.819533 View
ENSG00000096717 SIRT1 ENSG00000149823 VPS51 H. sapiens SSL Slorth 0.819155 View
ENSG00000096717 SIRT1 ENSG00000131507 NDFIP1 H. sapiens SSL Slorth 0.819008 View
ENSG00000096717 SIRT1 ENSG00000126247 CAPNS1 H. sapiens SSL Slorth 0.818995 View
ENSG00000096717 SIRT1 ENSG00000182504 CEP97 H. sapiens SSL Slorth 0.818841 View
ENSG00000096717 SIRT1 ENSG00000203668 CHML H. sapiens SSL Slorth 0.818816 View
ENSG00000089737 DDX24 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.818712 View
ENSG00000096717 SIRT1 ENSG00000169554 ZEB2 H. sapiens SSL Slorth 0.818656 View
ENSG00000096717 SIRT1 ENSG00000197905 TEAD4 H. sapiens SSL Slorth 0.818246 View
ENSG00000096717 SIRT1 ENSG00000105245 NUMBL H. sapiens SSL Slorth 0.818201 View
ENSG00000096717 SIRT1 ENSG00000167216 KATNAL2 H. sapiens SSL Slorth 0.818085 View
ENSG00000096717 SIRT1 ENSG00000262814 MRPL12 H. sapiens SSL Slorth 0.818005 View
ENSG00000096717 SIRT1 ENSG00000138071 ACTR2 H. sapiens SSL Slorth 0.817692 View
ENSG00000096717 SIRT1 ENSG00000198925 ATG9A H. sapiens SSL Slorth 0.817679 View
ENSG00000096717 SIRT1 ENSG00000196781 TLE1 H. sapiens SSL Slorth 0.817661 View
ENSG00000096717 SIRT1 ENSG00000130725 UBE2M H. sapiens SSL Slorth 0.817617 View
ENSG00000096717 SIRT1 ENSG00000102225 CDK16 H. sapiens SSL Slorth 0.817481 View
ENSG00000096717 SIRT1 ENSG00000196576 PLXNB2 H. sapiens SSL Slorth 0.817246 View
ENSG00000096717 SIRT1 ENSG00000115085 ZAP70 H. sapiens SSL Slorth 0.817076 View
ENSG00000096717 SIRT1 ENSG00000159459 UBR1 H. sapiens SSL Slorth 0.817037 View
ENSG00000096717 SIRT1 ENSG00000175093 SPSB4 H. sapiens SSL Slorth 0.816888 View
ENSG00000090861 AARS ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.816605 View
ENSG00000077254 USP33 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.815996 View
ENSG00000096717 SIRT1 ENSG00000168092 PAFAH1B2 H. sapiens SSL Slorth 0.815775 View
ENSG00000096717 SIRT1 ENSG00000123159 GIPC1 H. sapiens SSL Slorth 0.815769 View
ENSG00000034713 GABARAPL2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.815507 View
ENSG00000079785 DDX1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.815433 View
ENSG00000096717 SIRT1 ENSG00000136854 STXBP1 H. sapiens SSL Slorth 0.815431 View
ENSG00000096717 SIRT1 ENSG00000178188 SH2B1 H. sapiens SSL Slorth 0.8153 View
ENSG00000096717 SIRT1 ENSG00000198830 HMGN2 H. sapiens SSL Slorth 0.815221 View
ENSG00000096717 SIRT1 ENSG00000101558 VAPA H. sapiens SSL Slorth 0.815098 View