SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000198833 UBE2J1 H. sapiens SSL Slorth 0.828147 View
ENSG00000096717 SIRT1 ENSG00000112715 VEGFA H. sapiens SSL Slorth 0.827794 View
ENSG00000096717 SIRT1 ENSG00000197780 TAF13 H. sapiens SSL Slorth 0.827607 View
ENSG00000096717 SIRT1 ENSG00000196459 TRAPPC2 H. sapiens SSL Slorth 0.827556 View
ENSG00000096717 SIRT1 ENSG00000133275 CSNK1G2 H. sapiens SSL Slorth 0.827465 View
ENSG00000096717 SIRT1 ENSG00000136848 DAB2IP H. sapiens SSL Slorth 0.82733 View
ENSG00000096717 SIRT1 ENSG00000164985 PSIP1 H. sapiens SSL Slorth 0.827256 View
ENSG00000096717 SIRT1 ENSG00000186432 KPNA4 H. sapiens SSL Slorth 0.826799 View
ENSG00000096717 SIRT1 ENSG00000115350 POLE4 H. sapiens SSL Slorth 0.82621 View
ENSG00000096717 SIRT1 ENSG00000155363 MOV10 H. sapiens SSL Slorth 0.826175 View
ENSG00000096717 SIRT1 ENSG00000106245 BUD31 H. sapiens SSL Slorth 0.826006 View
ENSG00000096717 SIRT1 ENSG00000100417 PMM1 H. sapiens SSL Slorth 0.825956 View
ENSG00000096717 SIRT1 ENSG00000165458 INPPL1 H. sapiens SSL Slorth 0.825854 View
ENSG00000096717 SIRT1 ENSG00000163541 SUCLG1 H. sapiens SSL Slorth 0.825791 View
ENSG00000096717 SIRT1 ENSG00000113140 SPARC H. sapiens SSL Slorth 0.825769 View
ENSG00000096717 SIRT1 ENSG00000187266 EPOR H. sapiens SSL Slorth 0.825495 View
ENSG00000096717 SIRT1 ENSG00000113194 FAF2 H. sapiens SSL Slorth 0.825458 View
ENSG00000096717 SIRT1 ENSG00000160469 BRSK1 H. sapiens SSL Slorth 0.825438 View
ENSG00000055044 NOP58 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.824889 View
ENSG00000096717 SIRT1 ENSG00000108370 RGS9 H. sapiens SSL Slorth 0.82476 View
ENSG00000096717 SIRT1 ENSG00000213465 ARL2 H. sapiens SSL Slorth 0.824712 View
ENSG00000096717 SIRT1 ENSG00000171763 SPATA5L1 H. sapiens SSL Slorth 0.824543 View
ENSG00000096717 SIRT1 ENSG00000169891 REPS2 H. sapiens SSL Slorth 0.824394 View
ENSG00000088833 NSFL1C ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.824244 View
ENSG00000096717 SIRT1 ENSG00000118046 STK11 H. sapiens SSL Slorth 0.823953 View
ENSG00000078304 PPP2R5C ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.823919 View
ENSG00000096717 SIRT1 ENSG00000185236 RAB11B H. sapiens SSL Slorth 0.823613 View
ENSG00000043093 DCUN1D1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.823509 View
ENSG00000096717 SIRT1 ENSG00000266173 STRADA H. sapiens SSL Slorth 0.823459 View
ENSG00000004660 CAMKK1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.823382 View
ENSG00000096717 SIRT1 ENSG00000141384 TAF4B H. sapiens SSL Slorth 0.823346 View
ENSG00000096717 SIRT1 ENSG00000157514 TSC22D3 H. sapiens SSL Slorth 0.823182 View
ENSG00000096717 SIRT1 ENSG00000138160 KIF11 H. sapiens SSL Slorth 0.822911 View
ENSG00000096717 SIRT1 ENSG00000153071 DAB2 H. sapiens SSL Slorth 0.822544 View
ENSG00000096717 SIRT1 ENSG00000101057 MYBL2 H. sapiens SSL Slorth 0.822333 View
ENSG00000096717 SIRT1 ENSG00000115464 USP34 H. sapiens SSL Slorth 0.821967 View
ENSG00000096717 SIRT1 ENSG00000211455 STK38L H. sapiens SSL Slorth 0.821875 View
ENSG00000096717 SIRT1 ENSG00000114416 FXR1 H. sapiens SSL Slorth 0.821406 View
ENSG00000096717 SIRT1 ENSG00000184675 AMER1 H. sapiens SSL Slorth 0.821393 View
ENSG00000096717 SIRT1 ENSG00000119396 RAB14 H. sapiens SSL Slorth 0.821344 View