SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000166794 PPIB H. sapiens SSL Slorth 0.846518 View
ENSG00000049541 RFC2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.846041 View
ENSG00000096717 SIRT1 ENSG00000131462 TUBG1 H. sapiens SSL Slorth 0.84604 View
ENSG00000096717 SIRT1 ENSG00000156976 EIF4A2 H. sapiens SSL Slorth 0.845972 View
ENSG00000096717 SIRT1 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.845945 View
ENSG00000096717 SIRT1 ENSG00000174791 RIN1 H. sapiens SSL Slorth 0.845569 View
ENSG00000096717 SIRT1 ENSG00000166797 FAM96A H. sapiens SSL Slorth 0.845466 View
ENSG00000096717 SIRT1 ENSG00000110422 HIPK3 H. sapiens SSL Slorth 0.845322 View
ENSG00000096717 SIRT1 ENSG00000180228 PRKRA H. sapiens SSL Slorth 0.844704 View
ENSG00000096717 SIRT1 ENSG00000108106 UBE2S H. sapiens SSL Slorth 0.843816 View
ENSG00000077150 NFKB2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.843633 View
ENSG00000096717 SIRT1 ENSG00000173726 TOMM20 H. sapiens SSL Slorth 0.843577 View
ENSG00000096717 SIRT1 ENSG00000165506 DNAAF2 H. sapiens SSL Slorth 0.84308 View
ENSG00000095139 ARCN1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.842985 View
ENSG00000096717 SIRT1 ENSG00000100596 SPTLC2 H. sapiens SSL Slorth 0.842877 View
ENSG00000096717 SIRT1 ENSG00000196218 RYR1 H. sapiens SSL Slorth 0.842783 View
ENSG00000096717 SIRT1 ENSG00000103510 KAT8 H. sapiens SSL Slorth 0.842484 View
ENSG00000096717 SIRT1 ENSG00000182866 LCK H. sapiens SSL Slorth 0.842459 View
ENSG00000096717 SIRT1 ENSG00000175354 PTPN2 H. sapiens SSL Slorth 0.842298 View
ENSG00000096717 SIRT1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.842149 View
ENSG00000096717 SIRT1 ENSG00000101109 STK4 H. sapiens SSL Slorth 0.841953 View
ENSG00000096717 SIRT1 ENSG00000165684 SNAPC4 H. sapiens SSL Slorth 0.841794 View
ENSG00000096717 SIRT1 ENSG00000135069 PSAT1 H. sapiens SSL Slorth 0.841776 View
ENSG00000096717 SIRT1 ENSG00000100911 PSME2 H. sapiens SSL Slorth 0.841512 View
ENSG00000096717 SIRT1 ENSG00000106993 CDC37L1 H. sapiens SSL Slorth 0.841256 View
ENSG00000089154 GCN1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.84103 View
ENSG00000096717 SIRT1 ENSG00000169251 NMD3 H. sapiens SSL Slorth 0.841026 View
ENSG00000096717 SIRT1 ENSG00000197114 ZGPAT H. sapiens SSL Slorth 0.840667 View
ENSG00000096717 SIRT1 ENSG00000198791 CNOT7 H. sapiens SSL Slorth 0.840555 View
ENSG00000096717 SIRT1 ENSG00000163655 GMPS H. sapiens SSL Slorth 0.840459 View
ENSG00000096717 SIRT1 ENSG00000221914 PPP2R2A H. sapiens SSL Slorth 0.840086 View
ENSG00000096717 SIRT1 ENSG00000108384 RAD51C H. sapiens SSL Slorth 0.840059 View
ENSG00000096717 SIRT1 ENSG00000130826 DKC1 H. sapiens SSL Slorth 0.839841 View
ENSG00000070770 CSNK2A2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.839799 View
ENSG00000096717 SIRT1 ENSG00000101336 HCK H. sapiens SSL Slorth 0.839568 View
ENSG00000096717 SIRT1 ENSG00000213983 AP1G2 H. sapiens SSL Slorth 0.839344 View
ENSG00000096717 SIRT1 ENSG00000134333 LDHA H. sapiens SSL Slorth 0.839048 View
ENSG00000096717 SIRT1 ENSG00000166411 IDH3A H. sapiens SSL Slorth 0.838931 View
ENSG00000096717 SIRT1 ENSG00000132361 CLUH H. sapiens SSL Slorth 0.838284 View
ENSG00000096717 SIRT1 ENSG00000112039 FANCE H. sapiens SSL Slorth 0.837891 View