SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077063 CTTNBP2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.855658 View
ENSG00000096717 SIRT1 ENSG00000140829 DHX38 H. sapiens SSL Slorth 0.855315 View
ENSG00000096717 SIRT1 ENSG00000196262 PPIA H. sapiens SSL Slorth 0.855295 View
ENSG00000096717 SIRT1 ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.855138 View
ENSG00000096717 SIRT1 ENSG00000101367 MAPRE1 H. sapiens SSL Slorth 0.854982 View
ENSG00000096717 SIRT1 ENSG00000104825 NFKBIB H. sapiens SSL Slorth 0.854942 View
ENSG00000096717 SIRT1 ENSG00000107404 DVL1 H. sapiens SSL Slorth 0.85455 View
ENSG00000096717 SIRT1 ENSG00000136100 VPS36 H. sapiens SSL Slorth 0.854506 View
ENSG00000096717 SIRT1 ENSG00000126216 TUBGCP3 H. sapiens SSL Slorth 0.854364 View
ENSG00000096717 SIRT1 ENSG00000205220 PSMB10 H. sapiens SSL Slorth 0.854148 View
ENSG00000096717 SIRT1 ENSG00000189079 ARID2 H. sapiens SSL Slorth 0.854119 View
ENSG00000096717 SIRT1 ENSG00000152669 CCNO H. sapiens SSL Slorth 0.854052 View
ENSG00000088832 FKBP1A ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.85298 View
ENSG00000096717 SIRT1 ENSG00000119707 RBM25 H. sapiens SSL Slorth 0.852586 View
ENSG00000096717 SIRT1 ENSG00000107796 ACTA2 H. sapiens SSL Slorth 0.852151 View
ENSG00000096717 SIRT1 ENSG00000148943 LIN7C H. sapiens SSL Slorth 0.851557 View
ENSG00000028839 TBPL1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.851142 View
ENSG00000092847 AGO1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.850781 View
ENSG00000096717 SIRT1 ENSG00000164508 HIST1H2AA H. sapiens SSL Slorth 0.850733 View
ENSG00000096717 SIRT1 ENSG00000116266 STXBP3 H. sapiens SSL Slorth 0.850551 View
ENSG00000096717 SIRT1 ENSG00000136930 PSMB7 H. sapiens SSL Slorth 0.850152 View
ENSG00000096717 SIRT1 ENSG00000143878 RHOB H. sapiens SSL Slorth 0.849976 View
ENSG00000085415 SEH1L ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.849929 View
ENSG00000096717 SIRT1 ENSG00000165097 KDM1B H. sapiens SSL Slorth 0.849728 View
ENSG00000010256 UQCRC1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.849727 View
ENSG00000080608 PUM3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.849716 View
ENSG00000096717 SIRT1 ENSG00000113328 CCNG1 H. sapiens SSL Slorth 0.849378 View
ENSG00000096717 SIRT1 ENSG00000129824 RPS4Y1 H. sapiens SSL Slorth 0.849087 View
ENSG00000096717 SIRT1 ENSG00000134250 NOTCH2 H. sapiens SSL Slorth 0.848936 View
ENSG00000011304 PTBP1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.84889 View
ENSG00000096717 SIRT1 ENSG00000108559 NUP88 H. sapiens SSL Slorth 0.848652 View
ENSG00000096717 SIRT1 ENSG00000186716 BCR H. sapiens SSL Slorth 0.848607 View
ENSG00000096717 SIRT1 ENSG00000140538 NTRK3 H. sapiens SSL Slorth 0.848261 View
ENSG00000096717 SIRT1 ENSG00000204390 HSPA1L H. sapiens SSL Slorth 0.848175 View
ENSG00000096717 SIRT1 ENSG00000126524 SBDS H. sapiens SSL Slorth 0.847767 View
ENSG00000096717 SIRT1 ENSG00000141198 TOM1L1 H. sapiens SSL Slorth 0.847602 View
ENSG00000096717 SIRT1 ENSG00000143851 PTPN7 H. sapiens SSL Slorth 0.847213 View
ENSG00000096717 SIRT1 ENSG00000153233 PTPRR H. sapiens SSL Slorth 0.847213 View
ENSG00000096717 SIRT1 ENSG00000137413 TAF8 H. sapiens SSL Slorth 0.846699 View
ENSG00000096717 SIRT1 ENSG00000172409 CLP1 H. sapiens SSL Slorth 0.846628 View