FKBP1A - SIRT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FKBP1A	ENSG00000088832	No diseases in record	CYCLOSPORINE EVEROLIMUS PIMECROLIMUS SIROLIMUS TACROLIMUS TEMSIROLIMUS	peptidyl-prolyl cis-trans isomerase activity signal transducer activity transforming growth factor beta receptor binding protein binding macrolide binding FK506 binding enzyme binding Hsp70 protein binding type I transforming growth factor beta receptor binding protein homodimerization activity ion channel binding SMAD binding activin binding calcium channel inhibitor activity	FPR1 (S. cerevisiae) FK506-bp2 (D. melanogaster)
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)