SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000132612 VPS4A H. sapiens SSL Slorth 0.837853 View
ENSG00000096717 SIRT1 ENSG00000197930 ERO1A H. sapiens SSL Slorth 0.837517 View
ENSG00000096717 SIRT1 ENSG00000132912 DCTN4 H. sapiens SSL Slorth 0.837271 View
ENSG00000034152 MAP2K3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.837001 View
ENSG00000096717 SIRT1 ENSG00000139318 DUSP6 H. sapiens SSL Slorth 0.836765 View
ENSG00000096717 SIRT1 ENSG00000137815 RTF1 H. sapiens SSL Slorth 0.836728 View
ENSG00000096717 SIRT1 ENSG00000116473 RAP1A H. sapiens SSL Slorth 0.83667 View
ENSG00000051596 THOC3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.836518 View
ENSG00000069399 BCL3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.836245 View
ENSG00000096717 SIRT1 ENSG00000131828 PDHA1 H. sapiens SSL Slorth 0.835885 View
ENSG00000096717 SIRT1 ENSG00000169439 SDC2 H. sapiens SSL Slorth 0.835757 View
ENSG00000096717 SIRT1 ENSG00000139726 DENR H. sapiens SSL Slorth 0.83492 View
ENSG00000096717 SIRT1 ENSG00000115266 APC2 H. sapiens SSL Slorth 0.834852 View
ENSG00000096717 SIRT1 ENSG00000141985 SH3GL1 H. sapiens SSL Slorth 0.834844 View
ENSG00000096717 SIRT1 ENSG00000163636 PSMD6 H. sapiens SSL Slorth 0.834589 View
ENSG00000096717 SIRT1 ENSG00000171435 KSR2 H. sapiens SSL Slorth 0.834095 View
ENSG00000096717 SIRT1 ENSG00000122218 COPA H. sapiens SSL Slorth 0.833948 View
ENSG00000096717 SIRT1 ENSG00000175634 RPS6KB2 H. sapiens SSL Slorth 0.833924 View
ENSG00000057608 GDI2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.833748 View
ENSG00000096717 SIRT1 ENSG00000177105 RHOG H. sapiens SSL Slorth 0.833598 View
ENSG00000096717 SIRT1 ENSG00000115919 KYNU H. sapiens SSL Slorth 0.833335 View
ENSG00000096717 SIRT1 ENSG00000169188 APEX2 H. sapiens SSL Slorth 0.83311 View
ENSG00000096717 SIRT1 ENSG00000128731 HERC2 H. sapiens SSL Slorth 0.832887 View
ENSG00000096717 SIRT1 ENSG00000169174 PCSK9 H. sapiens SSL Slorth 0.832819 View
ENSG00000096717 SIRT1 ENSG00000111641 NOP2 H. sapiens SSL Slorth 0.832726 View
ENSG00000086758 HUWE1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.831806 View
ENSG00000096717 SIRT1 ENSG00000111725 PRKAB1 H. sapiens SSL Slorth 0.831261 View
ENSG00000096717 SIRT1 ENSG00000156587 UBE2L6 H. sapiens SSL Slorth 0.831252 View
ENSG00000096717 SIRT1 ENSG00000120833 SOCS2 H. sapiens SSL Slorth 0.831104 View
ENSG00000096717 SIRT1 ENSG00000166266 CUL5 H. sapiens SSL Slorth 0.830193 View
ENSG00000096717 SIRT1 ENSG00000134602 STK26 H. sapiens SSL Slorth 0.830049 View
ENSG00000096717 SIRT1 ENSG00000127152 BCL11B H. sapiens SSL Slorth 0.83003 View
ENSG00000096717 SIRT1 ENSG00000123975 CKS2 H. sapiens SSL Slorth 0.829696 View
ENSG00000096717 SIRT1 ENSG00000106355 LSM5 H. sapiens SSL Slorth 0.829674 View
ENSG00000096717 SIRT1 ENSG00000107672 NSMCE4A H. sapiens SSL Slorth 0.82905 View
ENSG00000096717 SIRT1 ENSG00000116016 EPAS1 H. sapiens SSL Slorth 0.828672 View
ENSG00000096717 SIRT1 ENSG00000148484 RSU1 H. sapiens SSL Slorth 0.828482 View
ENSG00000066027 PPP2R5A ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.828356 View
ENSG00000096717 SIRT1 ENSG00000175203 DCTN2 H. sapiens SSL Slorth 0.828305 View
ENSG00000096717 SIRT1 ENSG00000155438 NIFK H. sapiens SSL Slorth 0.828219 View