SIRT1 - RTF1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
RTF1	ENSG00000137815	No diseases in record	No drugs in record	transcription factor activity, RNA polymerase II transcription factor binding single-stranded DNA binding protein binding RNA polymerase II C-terminal domain phosphoserine binding DNA binding RNA binding histone methyltransferase activity (H3-K4 specific) mating type region replication fork barrier binding	RTF1 (S. cerevisiae) rtfo-1 (C. elegans) Rtf1 (D. melanogaster) CG31702 (D. melanogaster) CG31703 (D. melanogaster)