SIRT1 - MCM5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
MCM5	ENSG00000100297	No diseases in record	No drugs in record	DNA helicase activity chromatin binding DNA replication origin binding protein binding ATP binding hydrolase activity DNA binding single-stranded DNA binding helicase activity nucleotide binding single-stranded DNA-dependent ATP-dependent DNA helicase activity 3'-5' DNA helicase activity ATP-dependent DNA helicase activity	MCM5 (S. cerevisiae) mcm-5 (C. elegans) Mcm5 (D. melanogaster)