SIRT1 - HIST3H3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
HIST3H3	ENSG00000168148	No diseases in record	No drugs in record	protein binding nucleosomal DNA binding histone binding protein heterodimerization activity	HHT1 (S. cerevisiae) HHT2 (S. cerevisiae) his-13 (C. elegans) his-9 (C. elegans) his-25 (C. elegans) his-42 (C. elegans) his-59 (C. elegans) his-32 (C. elegans) his-45 (C. elegans) his-55 (C. elegans) his-63 (C. elegans) his-6 (C. elegans) his-49 (C. elegans) his-27 (C. elegans) his-17 (C. elegans) his-2 (C. elegans)