CFTR - KDM5A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CFTR	ENSG00000001626	No diseases in record	CROFELEMER IVACAFTOR LUMACAFTOR	chloride channel activity intracellular ATPase-gated chloride channel activity protein binding ATP binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride channel regulator activity chloride channel inhibitor activity enzyme binding PDZ domain binding ATPase-coupled anion transmembrane transporter activity	BPT1 (S. cerevisiae)
KDM5A	ENSG00000073614	AML	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors chromatin DNA binding histone demethylase activity	JHD2 (S. cerevisiae) rbr-2 (C. elegans)