CFTR - NR1D1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CFTR	ENSG00000001626	No diseases in record	CROFELEMER IVACAFTOR LUMACAFTOR	chloride channel activity intracellular ATPase-gated chloride channel activity protein binding ATP binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride channel regulator activity chloride channel inhibitor activity enzyme binding PDZ domain binding ATPase-coupled anion transmembrane transporter activity	BPT1 (S. cerevisiae)
NR1D1	ENSG00000126368	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription corepressor binding steroid hormone receptor activity transcription corepressor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding protein binding zinc ion binding heme binding transcription regulatory region DNA binding	Eip75B (D. melanogaster)