MSH6

ENSG00000116062 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0030983 mismatched DNA binding
GO:0035064 methylated histone binding
GO:0042803 protein homodimerization activity
GO:0000287 magnesium ion binding
GO:0000400 four-way junction DNA binding
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0032137 guanine/thymine mispair binding
GO:0032142 single guanine insertion binding
GO:0032143 single thymine insertion binding
GO:0032357 oxidized purine DNA binding
GO:0032405 MutLalpha complex binding
GO:0043531 ADP binding
GO:0003677 DNA binding
GO:0000166 nucleotide binding
GO:0032138 single base insertion or deletion binding
GO:0003684 damaged DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
endometrial
ovarian

Orthologs

Gene Organism
MSH6 S. cerevisiae
msh-6 C. elegans
Msh6 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000058729 RIOK2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.898941 View
ENSG00000099804 CDC34 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.89821 View
ENSG00000114767 RRP9 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.897877 View
ENSG00000078140 UBE2K ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.897018 View
ENSG00000101665 SMAD7 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.895714 View
ENSG00000105325 FZR1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.894114 View
ENSG00000036257 CUL3 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.893874 View
ENSG00000061938 TNK2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.892082 View
ENSG00000067560 RHOA ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.88952 View
ENSG00000110092 CCND1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.889502 View
ENSG00000080503 SMARCA2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.888004 View
ENSG00000079999 KEAP1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.887831 View
ENSG00000093009 CDC45 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.887743 View
ENSG00000102978 POLR2C ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.887311 View
ENSG00000113712 CSNK1A1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.886054 View
ENSG00000085840 ORC1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.88411 View
ENSG00000114867 EIF4G1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.884099 View
ENSG00000116062 MSH6 ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.882714 View
ENSG00000107581 EIF3A ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.882491 View
ENSG00000114423 CBLB ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.881605 View
ENSG00000099817 POLR2E ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.880371 View
ENSG00000100387 RBX1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.879764 View
ENSG00000077721 UBE2A ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.878526 View
ENSG00000072518 MARK2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.87773 View
ENSG00000110330 BIRC2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.877003 View
ENSG00000103479 RBL2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.874977 View
ENSG00000106462 EZH2 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.870307 View
ENSG00000280548 FBL ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.867186 View
ENSG00000073584 SMARCE1 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.866445 View
ENSG00000116062 MSH6 ENSG00000134086 VHL H. sapiens SSL Slorth 0.864799 View
ENSG00000100028 SNRPD3 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.863295 View
ENSG00000085832 EPS15 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.862874 View
ENSG00000116062 MSH6 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.862493 View
ENSG00000116062 MSH6 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.861343 View
ENSG00000116062 MSH6 ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.860004 View
ENSG00000074319 TSG101 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.859867 View
ENSG00000116062 MSH6 ENSG00000185359 HGS H. sapiens SSL Slorth 0.858636 View
ENSG00000116062 MSH6 ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.858042 View
ENSG00000023445 BIRC3 ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.856638 View
ENSG00000116062 MSH6 ENSG00000132170 PPARG H. sapiens SSL Slorth 0.855768 View