FBXW7 - MSH6

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
FBXW7 ENSG00000109670 colorectal
endometrial
T-ALL

No drugs in record

ubiquitin-protein transferase activity
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
phosphothreonine residue binding
ubiquitin-protein transferase activator activity
MET30 (S. cerevisiae)
sel-10 (C. elegans)
ago (D. melanogaster)
MSH6 ENSG00000116062 colorectal
endometrial
ovarian

No drugs in record

chromatin binding
protein binding
mismatched DNA binding
methylated histone binding
protein homodimerization activity
magnesium ion binding
four-way junction DNA binding
double-stranded DNA binding
ATP binding
ATPase activity
guanine/thymine mispair binding
single guanine insertion binding
single thymine insertion binding
oxidized purine DNA binding
MutLalpha complex binding
ADP binding
DNA binding
nucleotide binding
single base insertion or deletion binding
damaged DNA binding
MSH6 (S. cerevisiae)
msh-6 (C. elegans)
Msh6 (D. melanogaster)