MSH6 - SP1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MSH6	ENSG00000116062	colorectal endometrial ovarian	No drugs in record	chromatin binding protein binding mismatched DNA binding methylated histone binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding ATP binding ATPase activity guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding DNA binding nucleotide binding single base insertion or deletion binding damaged DNA binding	MSH6 (S. cerevisiae) msh-6 (C. elegans) Msh6 (D. melanogaster)
SP1	ENSG00000185591	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter sequence-specific DNA binding RNA polymerase II repressing transcription factor binding DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding histone acetyltransferase binding protein homodimerization activity histone deacetylase binding bHLH transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding HMG box domain binding RNA polymerase II transcription factor activity, sequence-specific DNA binding	No GO terms in record