MAPK1 - MSH6

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAPK1	ENSG00000100030	CLL ovarian mixed germ cell tumour cervical carcinoma	No drugs in record	phosphotyrosine residue binding DNA binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding transcription factor binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity phosphatase binding mitogen-activated protein kinase kinase kinase binding identical protein binding	FUS3 (S. cerevisiae) KSS1 (S. cerevisiae) mpk-1 (C. elegans) rl (D. melanogaster)
MSH6	ENSG00000116062	colorectal endometrial ovarian	No drugs in record	chromatin binding protein binding mismatched DNA binding methylated histone binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding ATP binding ATPase activity guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding DNA binding nucleotide binding single base insertion or deletion binding damaged DNA binding	MSH6 (S. cerevisiae) msh-6 (C. elegans) Msh6 (D. melanogaster)