MSH6 - MYC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MSH6	ENSG00000116062	colorectal endometrial ovarian	No drugs in record	chromatin binding protein binding mismatched DNA binding methylated histone binding protein homodimerization activity magnesium ion binding four-way junction DNA binding double-stranded DNA binding ATP binding ATPase activity guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding oxidized purine DNA binding MutLalpha complex binding ADP binding DNA binding nucleotide binding single base insertion or deletion binding damaged DNA binding	MSH6 (S. cerevisiae) msh-6 (C. elegans) Msh6 (D. melanogaster)
MYC	ENSG00000136997	Burkitt lymphoma amplified in other cancers B-CLL	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein complex binding protein dimerization activity repressing transcription factor binding E-box binding	No GO terms in record