ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000073614 KDM5A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969452 View
ENSG00000089685 BIRC5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969431 View
ENSG00000091831 ESR1 ENSG00000145715 RASA1 H. sapiens SDL Slorth 0.969425 View
ENSG00000091831 ESR1 ENSG00000133275 CSNK1G2 H. sapiens SDL Slorth 0.969423 View
ENSG00000091831 ESR1 ENSG00000151348 EXT2 H. sapiens SDL Slorth 0.969423 View
ENSG00000091831 ESR1 ENSG00000198898 CAPZA2 H. sapiens SDL Slorth 0.969421 View
ENSG00000091831 ESR1 ENSG00000166226 CCT2 H. sapiens SDL Slorth 0.969405 View
ENSG00000091831 ESR1 ENSG00000182521 TBPL2 H. sapiens SDL Slorth 0.969328 View
ENSG00000091831 ESR1 ENSG00000130396 AFDN H. sapiens SDL Slorth 0.969326 View
ENSG00000091831 ESR1 ENSG00000168002 POLR2G H. sapiens SDL Slorth 0.969323 View
ENSG00000066136 NFYC ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969302 View
ENSG00000091831 ESR1 ENSG00000116830 TTF2 H. sapiens SDL Slorth 0.9693 View
ENSG00000010244 ZNF207 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.969262 View
ENSG00000091831 ESR1 ENSG00000198055 GRK6 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000145416 MARCH1 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000186625 KATNA1 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000198492 YTHDF2 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000138646 HERC5 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000101210 EEF1A2 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000169118 CSNK1G1 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000213782 DDX47 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000101337 TM9SF4 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000141279 NPEPPS H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000137285 TUBB2B H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000139514 SLC7A1 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000198218 QRICH1 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000182220 ATP6AP2 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000144476 ACKR3 H. sapiens SDL Slorth 0.969237 View
ENSG00000091831 ESR1 ENSG00000163840 DTX3L H. sapiens SDL Slorth 0.969227 View
ENSG00000091831 ESR1 ENSG00000142949 PTPRF H. sapiens SDL Slorth 0.969216 View
ENSG00000091831 ESR1 ENSG00000167670 CHAF1A H. sapiens SDL Slorth 0.969203 View
ENSG00000091831 ESR1 ENSG00000196712 NF1 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000143545 RAB13 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000117143 UAP1 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000165304 MELK H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000188042 ARL4C H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000162616 DNAJB4 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000105281 SLC1A5 H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000138182 KIF20B H. sapiens SDL Slorth 0.969189 View
ENSG00000091831 ESR1 ENSG00000118193 KIF14 H. sapiens SDL Slorth 0.969189 View