ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000029639 TFB1M ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972033 View
ENSG00000091831 ESR1 ENSG00000133835 HSD17B4 H. sapiens SDL Slorth 0.972018 View
ENSG00000001167 NFYA ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972003 View
ENSG00000091831 ESR1 ENSG00000108468 CBX1 H. sapiens SDL Slorth 0.971986 View
ENSG00000091831 ESR1 ENSG00000131653 TRAF7 H. sapiens SDL Slorth 0.971963 View
ENSG00000091831 ESR1 ENSG00000160867 FGFR4 H. sapiens SDL Slorth 0.971924 View
ENSG00000091831 ESR1 ENSG00000163399 ATP1A1 H. sapiens SDL Slorth 0.971916 View
ENSG00000007968 E2F2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971915 View
ENSG00000091831 ESR1 ENSG00000115866 DARS H. sapiens SDL Slorth 0.9719 View
ENSG00000091831 ESR1 ENSG00000125630 POLR1B H. sapiens SDL Slorth 0.971899 View
ENSG00000091831 ESR1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.971882 View
ENSG00000032444 PNPLA6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971834 View
ENSG00000011485 PPP5C ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971778 View
ENSG00000091831 ESR1 ENSG00000130787 HIP1R H. sapiens SDL Slorth 0.971773 View
ENSG00000091831 ESR1 ENSG00000158092 NCK1 H. sapiens SDL Slorth 0.971758 View
ENSG00000033327 GAB2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971739 View
ENSG00000091831 ESR1 ENSG00000139613 SMARCC2 H. sapiens SDL Slorth 0.971677 View
ENSG00000077254 USP33 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971666 View
ENSG00000091831 ESR1 ENSG00000147573 TRIM55 H. sapiens SDL Slorth 0.97166 View
ENSG00000068971 PPP2R5B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971591 View
ENSG00000091831 ESR1 ENSG00000184009 ACTG1 H. sapiens SDL Slorth 0.971562 View
ENSG00000090432 MUL1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97156 View
ENSG00000091831 ESR1 ENSG00000108094 CUL2 H. sapiens SDL Slorth 0.971525 View
ENSG00000044115 CTNNA1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97152 View
ENSG00000091831 ESR1 ENSG00000123416 TUBA1B H. sapiens SDL Slorth 0.971516 View
ENSG00000091831 ESR1 ENSG00000109458 GAB1 H. sapiens SDL Slorth 0.971485 View
ENSG00000091831 ESR1 ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.971455 View
ENSG00000068305 MEF2A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971441 View
ENSG00000091831 ESR1 ENSG00000133895 MEN1 H. sapiens SDL Slorth 0.971414 View
ENSG00000091831 ESR1 ENSG00000132002 DNAJB1 H. sapiens SDL Slorth 0.971405 View
ENSG00000055609 KMT2C ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971382 View
ENSG00000091831 ESR1 ENSG00000110092 CCND1 H. sapiens SDL Slorth 0.971356 View
ENSG00000091831 ESR1 ENSG00000157554 ERG H. sapiens SDL Slorth 0.971356 View
ENSG00000091831 ESR1 ENSG00000175334 BANF1 H. sapiens SDL Slorth 0.971346 View
ENSG00000075651 PLD1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971346 View
ENSG00000091831 ESR1 ENSG00000143093 STRIP1 H. sapiens SDL Slorth 0.971295 View
ENSG00000062650 WAPL ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971293 View
ENSG00000091831 ESR1 ENSG00000169045 HNRNPH1 H. sapiens SDL Slorth 0.971287 View
ENSG00000091831 ESR1 ENSG00000253729 PRKDC H. sapiens SDL Slorth 0.971267 View
ENSG00000044574 HSPA5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.971267 View