ESR1 - HSD17B4

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ESR1	ENSG00000091831	breast	BAZEDOXIFENE DIENESTROL DIETHYLSTILBESTROL DIETHYLSTILBESTROL DIPHOSPHATE ENCLOMIPHENE ESTRADIOL ESTRADIOL ACETATE ESTRADIOL CYPIONATE ESTRADIOL VALERATE ESTROGENS, CONJUGATED ESTROGENS, CONJUGATED SYNTHETIC A ESTROGENS, ESTERIFIED ESTRONE ESTRONE SULFURIC ACID ETHINYL ESTRADIOL FULVESTRANT MESTRANOL OSPEMIFENE POLYESTRADIOL PHOSPHATE QUINESTROL RALOXIFENE SYNTHETIC CONJUGATED ESTROGENS, B TAMOXIFEN TOREMIFENE	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity steroid binding protein binding beta-catenin binding transcription factor binding zinc ion binding enzyme binding nitric-oxide synthase regulator activity estrogen receptor activity estrogen response element binding RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding identical protein binding ATPase binding	No GO terms in record
HSD17B4	ENSG00000133835	No diseases in record	No drugs in record	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity 3-hydroxyacyl-CoA dehydrogenase activity isocitrate dehydrogenase activity mevaldate reductase activity receptor binding gluconate dehydrogenase activity long-chain-enoyl-CoA hydratase activity isomerase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-CH group of donors 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity protein homodimerization activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 3-ketoglucose-reductase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity	FOX2 (S. cerevisiae)