ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000025796 SEC63 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972792 View
ENSG00000090020 SLC9A1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972726 View
ENSG00000089094 KDM2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972725 View
ENSG00000084072 PPIE ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972715 View
ENSG00000076604 TRAF4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972697 View
ENSG00000091831 ESR1 ENSG00000114302 PRKAR2A H. sapiens SDL Slorth 0.972685 View
ENSG00000091831 ESR1 ENSG00000137834 SMAD6 H. sapiens SDL Slorth 0.972668 View
ENSG00000091831 ESR1 ENSG00000134352 IL6ST H. sapiens SDL Slorth 0.972655 View
ENSG00000091831 ESR1 ENSG00000128512 DOCK4 H. sapiens SDL Slorth 0.972627 View
ENSG00000004897 CDC27 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972606 View
ENSG00000076555 ACACB ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972603 View
ENSG00000091831 ESR1 ENSG00000163104 SMARCAD1 H. sapiens SDL Slorth 0.972601 View
ENSG00000091831 ESR1 ENSG00000198677 TTC37 H. sapiens SDL Slorth 0.972578 View
ENSG00000091831 ESR1 ENSG00000166888 STAT6 H. sapiens SDL Slorth 0.972569 View
ENSG00000091831 ESR1 ENSG00000104320 NBN H. sapiens SDL Slorth 0.972522 View
ENSG00000091831 ESR1 ENSG00000185344 ATP6V0A2 H. sapiens SDL Slorth 0.972515 View
ENSG00000091831 ESR1 ENSG00000204842 ATXN2 H. sapiens SDL Slorth 0.972484 View
ENSG00000091831 ESR1 ENSG00000176102 CSTF3 H. sapiens SDL Slorth 0.972481 View
ENSG00000091831 ESR1 ENSG00000184304 PRKD1 H. sapiens SDL Slorth 0.972427 View
ENSG00000091831 ESR1 ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.972394 View
ENSG00000080224 EPHA6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972361 View
ENSG00000091831 ESR1 ENSG00000205726 ITSN1 H. sapiens SDL Slorth 0.972338 View
ENSG00000091831 ESR1 ENSG00000181788 SIAH2 H. sapiens SDL Slorth 0.972318 View
ENSG00000089289 IGBP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972312 View
ENSG00000091831 ESR1 ENSG00000159259 CHAF1B H. sapiens SDL Slorth 0.972257 View
ENSG00000091831 ESR1 ENSG00000137710 RDX H. sapiens SDL Slorth 0.972237 View
ENSG00000091831 ESR1 ENSG00000176014 TUBB6 H. sapiens SDL Slorth 0.972209 View
ENSG00000076344 RGS11 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972189 View
ENSG00000091831 ESR1 ENSG00000177054 ZDHHC13 H. sapiens SDL Slorth 0.972182 View
ENSG00000091831 ESR1 ENSG00000162407 PLPP3 H. sapiens SDL Slorth 0.972182 View
ENSG00000091831 ESR1 ENSG00000141458 NPC1 H. sapiens SDL Slorth 0.972182 View
ENSG00000091831 ESR1 ENSG00000100297 MCM5 H. sapiens SDL Slorth 0.972174 View
ENSG00000091831 ESR1 ENSG00000164171 ITGA2 H. sapiens SDL Slorth 0.972168 View
ENSG00000025800 KPNA6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972164 View
ENSG00000091831 ESR1 ENSG00000149136 SSRP1 H. sapiens SDL Slorth 0.972145 View
ENSG00000023287 RB1CC1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.972138 View
ENSG00000091831 ESR1 ENSG00000169139 UBE2V2 H. sapiens SDL Slorth 0.972119 View
ENSG00000091831 ESR1 ENSG00000100345 MYH9 H. sapiens SDL Slorth 0.972112 View
ENSG00000091831 ESR1 ENSG00000197879 MYO1C H. sapiens SDL Slorth 0.972061 View
ENSG00000091831 ESR1 ENSG00000113575 PPP2CA H. sapiens SDL Slorth 0.972053 View