ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000141367 CLTC H. sapiens SDL Slorth 0.975555 View
ENSG00000091831 ESR1 ENSG00000172534 HCFC1 H. sapiens SDL Slorth 0.975542 View
ENSG00000091831 ESR1 ENSG00000137270 GCM1 H. sapiens SDL Slorth 0.975521 View
ENSG00000091831 ESR1 ENSG00000157823 AP3S2 H. sapiens SDL Slorth 0.975518 View
ENSG00000091831 ESR1 ENSG00000171791 BCL2 H. sapiens SDL Slorth 0.975414 View
ENSG00000038382 TRIO ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975412 View
ENSG00000074219 TEAD2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975392 View
ENSG00000091831 ESR1 ENSG00000183763 TRAIP H. sapiens SDL Slorth 0.975376 View
ENSG00000091831 ESR1 ENSG00000142192 APP H. sapiens SDL Slorth 0.975333 View
ENSG00000091831 ESR1 ENSG00000107485 GATA3 H. sapiens SDL Slorth 0.975299 View
ENSG00000091831 ESR1 ENSG00000148737 TCF7L2 H. sapiens SDL Slorth 0.975297 View
ENSG00000091831 ESR1 ENSG00000127527 EPS15L1 H. sapiens SDL Slorth 0.975288 View
ENSG00000091831 ESR1 ENSG00000106089 STX1A H. sapiens SDL Slorth 0.975203 View
ENSG00000091831 ESR1 ENSG00000184634 MED12 H. sapiens SDL Slorth 0.975197 View
ENSG00000091831 ESR1 ENSG00000167513 CDT1 H. sapiens SDL Slorth 0.975181 View
ENSG00000091831 ESR1 ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.975167 View
ENSG00000091831 ESR1 ENSG00000132005 RFX1 H. sapiens SDL Slorth 0.975065 View
ENSG00000091831 ESR1 ENSG00000115884 SDC1 H. sapiens SDL Slorth 0.975062 View
ENSG00000091831 ESR1 ENSG00000147133 TAF1 H. sapiens SDL Slorth 0.975061 View
ENSG00000007171 NOS2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975048 View
ENSG00000072736 NFATC3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975044 View
ENSG00000088256 GNA11 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975043 View
ENSG00000021826 CPS1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975039 View
ENSG00000014216 CAPN1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975024 View
ENSG00000091831 ESR1 ENSG00000198925 ATG9A H. sapiens SDL Slorth 0.974994 View
ENSG00000091831 ESR1 ENSG00000112984 KIF20A H. sapiens SDL Slorth 0.97499 View
ENSG00000002834 LASP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.974902 View
ENSG00000091831 ESR1 ENSG00000211456 SACM1L H. sapiens SDL Slorth 0.974872 View
ENSG00000091831 ESR1 ENSG00000171241 SHCBP1 H. sapiens SDL Slorth 0.974872 View
ENSG00000091831 ESR1 ENSG00000162236 STX5 H. sapiens SDL Slorth 0.974821 View
ENSG00000091831 ESR1 ENSG00000122566 HNRNPA2B1 H. sapiens SDL Slorth 0.974819 View
ENSG00000091831 ESR1 ENSG00000146457 WTAP H. sapiens SDL Slorth 0.974799 View
ENSG00000078304 PPP2R5C ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97477 View
ENSG00000091831 ESR1 ENSG00000273841 TAF9 H. sapiens SDL Slorth 0.974752 View
ENSG00000091831 ESR1 ENSG00000119396 RAB14 H. sapiens SDL Slorth 0.974746 View
ENSG00000091831 ESR1 ENSG00000157087 ATP2B2 H. sapiens SDL Slorth 0.974746 View
ENSG00000091831 ESR1 ENSG00000172531 PPP1CA H. sapiens SDL Slorth 0.974679 View
ENSG00000091831 ESR1 ENSG00000145703 IQGAP2 H. sapiens SDL Slorth 0.974677 View
ENSG00000091831 ESR1 ENSG00000170525 PFKFB3 H. sapiens SDL Slorth 0.974662 View
ENSG00000091831 ESR1 ENSG00000170004 CHD3 H. sapiens SDL Slorth 0.97465 View