ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000041982 TNC ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977559 View
ENSG00000091831 ESR1 ENSG00000145349 CAMK2D H. sapiens SDL Slorth 0.977536 View
ENSG00000091831 ESR1 ENSG00000100485 SOS2 H. sapiens SDL Slorth 0.977524 View
ENSG00000091831 ESR1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977512 View
ENSG00000091831 ESR1 ENSG00000128881 TTBK2 H. sapiens SDL Slorth 0.977484 View
ENSG00000091831 ESR1 ENSG00000175216 CKAP5 H. sapiens SDL Slorth 0.977477 View
ENSG00000082805 ERC1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977467 View
ENSG00000091831 ESR1 ENSG00000111581 NUP107 H. sapiens SDL Slorth 0.977455 View
ENSG00000091831 ESR1 ENSG00000108861 DUSP3 H. sapiens SDL Slorth 0.977454 View
ENSG00000091831 ESR1 ENSG00000092201 SUPT16H H. sapiens SDL Slorth 0.97743 View
ENSG00000091831 ESR1 ENSG00000101197 BIRC7 H. sapiens SDL Slorth 0.977429 View
ENSG00000091831 ESR1 ENSG00000173848 NET1 H. sapiens SDL Slorth 0.97741 View
ENSG00000091831 ESR1 ENSG00000172115 CYCS H. sapiens SDL Slorth 0.977404 View
ENSG00000091831 ESR1 ENSG00000101871 MID1 H. sapiens SDL Slorth 0.977384 View
ENSG00000091831 ESR1 ENSG00000163602 RYBP H. sapiens SDL Slorth 0.977353 View
ENSG00000091831 ESR1 ENSG00000103126 AXIN1 H. sapiens SDL Slorth 0.977298 View
ENSG00000091831 ESR1 ENSG00000152137 HSPB8 H. sapiens SDL Slorth 0.977288 View
ENSG00000091831 ESR1 ENSG00000179776 CDH5 H. sapiens SDL Slorth 0.97728 View
ENSG00000091831 ESR1 ENSG00000132170 PPARG H. sapiens SDL Slorth 0.977268 View
ENSG00000091831 ESR1 ENSG00000107105 ELAVL2 H. sapiens SDL Slorth 0.977264 View
ENSG00000091831 ESR1 ENSG00000166333 ILK H. sapiens SDL Slorth 0.977258 View
ENSG00000091831 ESR1 ENSG00000105656 ELL H. sapiens SDL Slorth 0.97724 View
ENSG00000091831 ESR1 ENSG00000183735 TBK1 H. sapiens SDL Slorth 0.977235 View
ENSG00000091831 ESR1 ENSG00000143379 SETDB1 H. sapiens SDL Slorth 0.977226 View
ENSG00000091831 ESR1 ENSG00000103363 TCEB2 H. sapiens SDL Slorth 0.977219 View
ENSG00000080371 RAB21 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977207 View
ENSG00000091831 ESR1 ENSG00000126457 PRMT1 H. sapiens SDL Slorth 0.977206 View
ENSG00000091831 ESR1 ENSG00000107201 DDX58 H. sapiens SDL Slorth 0.977192 View
ENSG00000091831 ESR1 ENSG00000132781 MUTYH H. sapiens SDL Slorth 0.977164 View
ENSG00000091831 ESR1 ENSG00000103966 EHD4 H. sapiens SDL Slorth 0.97714 View
ENSG00000091831 ESR1 ENSG00000112339 HBS1L H. sapiens SDL Slorth 0.977131 View
ENSG00000091831 ESR1 ENSG00000139083 ETV6 H. sapiens SDL Slorth 0.977122 View
ENSG00000090061 CCNK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.9771 View
ENSG00000091831 ESR1 ENSG00000101096 NFATC2 H. sapiens SDL Slorth 0.977074 View
ENSG00000091831 ESR1 ENSG00000170027 YWHAG H. sapiens SDL Slorth 0.977045 View
ENSG00000091831 ESR1 ENSG00000133226 SRRM1 H. sapiens SDL Slorth 0.977014 View
ENSG00000079432 CIC ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977001 View
ENSG00000058404 CAMK2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.977001 View
ENSG00000091831 ESR1 ENSG00000137055 PLAA H. sapiens SDL Slorth 0.976982 View
ENSG00000091831 ESR1 ENSG00000107223 EDF1 H. sapiens SDL Slorth 0.976956 View