ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000163558 PRKCI H. sapiens SDL Slorth 0.978681 View
ENSG00000091831 ESR1 ENSG00000176105 YES1 H. sapiens SDL Slorth 0.978675 View
ENSG00000091831 ESR1 ENSG00000125870 SNRPB2 H. sapiens SDL Slorth 0.978671 View
ENSG00000091831 ESR1 ENSG00000170348 TMED10 H. sapiens SDL Slorth 0.978669 View
ENSG00000091831 ESR1 ENSG00000131747 TOP2A H. sapiens SDL Slorth 0.978626 View
ENSG00000091831 ESR1 ENSG00000161202 DVL3 H. sapiens SDL Slorth 0.978596 View
ENSG00000091831 ESR1 ENSG00000198554 WDHD1 H. sapiens SDL Slorth 0.978569 View
ENSG00000091831 ESR1 ENSG00000124193 SRSF6 H. sapiens SDL Slorth 0.978555 View
ENSG00000073712 FERMT2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978549 View
ENSG00000091831 ESR1 ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.978515 View
ENSG00000081913 PHLPP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978506 View
ENSG00000091831 ESR1 ENSG00000133119 RFC3 H. sapiens SDL Slorth 0.978504 View
ENSG00000083857 FAT1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.9785 View
ENSG00000091831 ESR1 ENSG00000137267 TUBB2A H. sapiens SDL Slorth 0.97848 View
ENSG00000073060 SCARB1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978471 View
ENSG00000091831 ESR1 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.978446 View
ENSG00000090621 PABPC4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978445 View
ENSG00000000938 FGR ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978444 View
ENSG00000091831 ESR1 ENSG00000161270 NPHS1 H. sapiens SDL Slorth 0.978437 View
ENSG00000091831 ESR1 ENSG00000168488 ATXN2L H. sapiens SDL Slorth 0.978399 View
ENSG00000091831 ESR1 ENSG00000152684 PELO H. sapiens SDL Slorth 0.978399 View
ENSG00000091831 ESR1 ENSG00000164695 CHMP4C H. sapiens SDL Slorth 0.978393 View
ENSG00000091831 ESR1 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.97838 View
ENSG00000091831 ESR1 ENSG00000107295 SH3GL2 H. sapiens SDL Slorth 0.978365 View
ENSG00000091831 ESR1 ENSG00000124486 USP9X H. sapiens SDL Slorth 0.978365 View
ENSG00000091831 ESR1 ENSG00000108387 SEPT4 H. sapiens SDL Slorth 0.978365 View
ENSG00000091831 ESR1 ENSG00000099940 SNAP29 H. sapiens SDL Slorth 0.978364 View
ENSG00000091831 ESR1 ENSG00000155508 CNOT8 H. sapiens SDL Slorth 0.978353 View
ENSG00000091831 ESR1 ENSG00000138758 SEPT11 H. sapiens SDL Slorth 0.978334 View
ENSG00000011007 TCEB3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978321 View
ENSG00000091831 ESR1 ENSG00000116016 EPAS1 H. sapiens SDL Slorth 0.97832 View
ENSG00000091831 ESR1 ENSG00000162409 PRKAA2 H. sapiens SDL Slorth 0.97832 View
ENSG00000091831 ESR1 ENSG00000130726 TRIM28 H. sapiens SDL Slorth 0.978314 View
ENSG00000055917 PUM2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978306 View
ENSG00000091831 ESR1 ENSG00000100227 POLDIP3 H. sapiens SDL Slorth 0.978295 View
ENSG00000091831 ESR1 ENSG00000120063 GNA13 H. sapiens SDL Slorth 0.978294 View
ENSG00000091831 ESR1 ENSG00000092847 AGO1 H. sapiens SDL Slorth 0.978258 View
ENSG00000091831 ESR1 ENSG00000115266 APC2 H. sapiens SDL Slorth 0.978241 View
ENSG00000067225 PKM ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978236 View
ENSG00000061676 NCKAP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.978233 View