ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000058668 ATP2B4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976234 View
ENSG00000091831 ESR1 ENSG00000104881 PPP1R13L H. sapiens SDL Slorth 0.976212 View
ENSG00000005882 PDK2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976204 View
ENSG00000065526 SPEN ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976198 View
ENSG00000091831 ESR1 ENSG00000100311 PDGFB H. sapiens SDL Slorth 0.976197 View
ENSG00000091831 ESR1 ENSG00000143970 ASXL2 H. sapiens SDL Slorth 0.976177 View
ENSG00000091831 ESR1 ENSG00000100721 TCL1A H. sapiens SDL Slorth 0.976158 View
ENSG00000091831 ESR1 ENSG00000123908 AGO2 H. sapiens SDL Slorth 0.976157 View
ENSG00000049768 FOXP3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976142 View
ENSG00000091831 ESR1 ENSG00000164885 CDK5 H. sapiens SDL Slorth 0.976121 View
ENSG00000066032 CTNNA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976115 View
ENSG00000091831 ESR1 ENSG00000106211 HSPB1 H. sapiens SDL Slorth 0.976097 View
ENSG00000091831 ESR1 ENSG00000148606 POLR3A H. sapiens SDL Slorth 0.976092 View
ENSG00000091831 ESR1 ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.976046 View
ENSG00000005961 ITGA2B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976004 View
ENSG00000091831 ESR1 ENSG00000099804 CDC34 H. sapiens SDL Slorth 0.976003 View
ENSG00000091831 ESR1 ENSG00000131236 CAP1 H. sapiens SDL Slorth 0.975998 View
ENSG00000091831 ESR1 ENSG00000166900 STX3 H. sapiens SDL Slorth 0.975977 View
ENSG00000091831 ESR1 ENSG00000173757 STAT5B H. sapiens SDL Slorth 0.975958 View
ENSG00000010671 BTK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97595 View
ENSG00000091831 ESR1 ENSG00000137497 NUMA1 H. sapiens SDL Slorth 0.975915 View
ENSG00000091831 ESR1 ENSG00000140455 USP3 H. sapiens SDL Slorth 0.9759 View
ENSG00000091831 ESR1 ENSG00000092820 EZR H. sapiens SDL Slorth 0.975886 View
ENSG00000091831 ESR1 ENSG00000163482 STK36 H. sapiens SDL Slorth 0.97587 View
ENSG00000091831 ESR1 ENSG00000102981 PARD6A H. sapiens SDL Slorth 0.975831 View
ENSG00000091831 ESR1 ENSG00000184481 FOXO4 H. sapiens SDL Slorth 0.97583 View
ENSG00000085733 CTTN ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975812 View
ENSG00000091831 ESR1 ENSG00000125977 EIF2S2 H. sapiens SDL Slorth 0.97578 View
ENSG00000091831 ESR1 ENSG00000213281 NRAS H. sapiens SDL Slorth 0.975726 View
ENSG00000091831 ESR1 ENSG00000177889 UBE2N H. sapiens SDL Slorth 0.975719 View
ENSG00000091831 ESR1 ENSG00000115091 ACTR3 H. sapiens SDL Slorth 0.975692 View
ENSG00000091831 ESR1 ENSG00000097046 CDC7 H. sapiens SDL Slorth 0.97569 View
ENSG00000091831 ESR1 ENSG00000198911 SREBF2 H. sapiens SDL Slorth 0.975682 View
ENSG00000012983 MAP4K5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975675 View
ENSG00000091831 ESR1 ENSG00000128908 INO80 H. sapiens SDL Slorth 0.975639 View
ENSG00000091831 ESR1 ENSG00000144566 RAB5A H. sapiens SDL Slorth 0.975629 View
ENSG00000025434 NR1H3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975619 View
ENSG00000066044 ELAVL1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975587 View
ENSG00000071575 TRIB2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975581 View
ENSG00000089250 NOS1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.975568 View