ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000137807 KIF23 H. sapiens SDL Slorth 0.980085 View
ENSG00000091831 ESR1 ENSG00000140983 RHOT2 H. sapiens SDL Slorth 0.980085 View
ENSG00000091831 ESR1 ENSG00000196586 MYO6 H. sapiens SDL Slorth 0.980074 View
ENSG00000091831 ESR1 ENSG00000116044 NFE2L2 H. sapiens SDL Slorth 0.980073 View
ENSG00000091831 ESR1 ENSG00000114126 TFDP2 H. sapiens SDL Slorth 0.980069 View
ENSG00000091831 ESR1 ENSG00000204217 BMPR2 H. sapiens SDL Slorth 0.980015 View
ENSG00000091831 ESR1 ENSG00000140678 ITGAX H. sapiens SDL Slorth 0.979995 View
ENSG00000005844 ITGAL ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979986 View
ENSG00000091831 ESR1 ENSG00000163939 PBRM1 H. sapiens SDL Slorth 0.979971 View
ENSG00000090889 KIF4A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979967 View
ENSG00000091831 ESR1 ENSG00000131462 TUBG1 H. sapiens SDL Slorth 0.979961 View
ENSG00000091831 ESR1 ENSG00000132356 PRKAA1 H. sapiens SDL Slorth 0.979949 View
ENSG00000091831 ESR1 ENSG00000124181 PLCG1 H. sapiens SDL Slorth 0.979918 View
ENSG00000091831 ESR1 ENSG00000197579 TOPORS H. sapiens SDL Slorth 0.979898 View
ENSG00000091831 ESR1 ENSG00000121671 CRY2 H. sapiens SDL Slorth 0.979894 View
ENSG00000035928 RFC1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979888 View
ENSG00000091831 ESR1 ENSG00000117408 IPO13 H. sapiens SDL Slorth 0.979878 View
ENSG00000091831 ESR1 ENSG00000247077 PGAM5 H. sapiens SDL Slorth 0.979872 View
ENSG00000091831 ESR1 ENSG00000172315 TP53RK H. sapiens SDL Slorth 0.979862 View
ENSG00000091831 ESR1 ENSG00000169100 SLC25A6 H. sapiens SDL Slorth 0.979856 View
ENSG00000069345 DNAJA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979851 View
ENSG00000091831 ESR1 ENSG00000112335 SNX3 H. sapiens SDL Slorth 0.979825 View
ENSG00000091831 ESR1 ENSG00000116688 MFN2 H. sapiens SDL Slorth 0.979821 View
ENSG00000091831 ESR1 ENSG00000104907 TRMT1 H. sapiens SDL Slorth 0.979798 View
ENSG00000079337 RAPGEF3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979775 View
ENSG00000091831 ESR1 ENSG00000175029 CTBP2 H. sapiens SDL Slorth 0.979769 View
ENSG00000077684 JADE1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979759 View
ENSG00000091831 ESR1 ENSG00000167553 TUBA1C H. sapiens SDL Slorth 0.979752 View
ENSG00000091831 ESR1 ENSG00000141556 TBCD H. sapiens SDL Slorth 0.979742 View
ENSG00000091831 ESR1 ENSG00000107341 UBE2R2 H. sapiens SDL Slorth 0.979736 View
ENSG00000091831 ESR1 ENSG00000101412 E2F1 H. sapiens SDL Slorth 0.979726 View
ENSG00000091831 ESR1 ENSG00000124571 XPO5 H. sapiens SDL Slorth 0.97972 View
ENSG00000081377 CDC14B ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979711 View
ENSG00000091831 ESR1 ENSG00000115163 CENPA H. sapiens SDL Slorth 0.979709 View
ENSG00000007908 SELE ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.979705 View
ENSG00000091831 ESR1 ENSG00000163132 MSX1 H. sapiens SDL Slorth 0.979687 View
ENSG00000091831 ESR1 ENSG00000115170 ACVR1 H. sapiens SDL Slorth 0.979685 View
ENSG00000091831 ESR1 ENSG00000112079 STK38 H. sapiens SDL Slorth 0.979683 View
ENSG00000091831 ESR1 ENSG00000100722 ZC3H14 H. sapiens SDL Slorth 0.979675 View
ENSG00000091831 ESR1 ENSG00000188021 UBQLN2 H. sapiens SDL Slorth 0.979655 View