ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000080503 SMARCA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970336 View
ENSG00000091831 ESR1 ENSG00000103522 IL21R H. sapiens SDL Slorth 0.970328 View
ENSG00000091831 ESR1 ENSG00000178028 DMAP1 H. sapiens SDL Slorth 0.970311 View
ENSG00000083168 KAT6A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970301 View
ENSG00000091831 ESR1 ENSG00000171793 CTPS1 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000169067 ACTBL2 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000116791 CRYZ H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000148408 CACNA1B H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000145860 RNF145 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000108828 VAT1 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000135924 DNAJB2 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000168806 LCMT2 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000166128 RAB8B H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000099992 TBC1D10A H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000165406 MARCH8 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000173218 VANGL1 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000172890 NADSYN1 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000159399 HK2 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000148834 GSTO1 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000188641 DPYD H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000140526 ABHD2 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000123338 NCKAP1L H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000189241 TSPYL1 H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000186111 PIP5K1C H. sapiens SDL Slorth 0.9703 View
ENSG00000091831 ESR1 ENSG00000109220 CHIC2 H. sapiens SDL Slorth 0.9703 View
ENSG00000012504 NR1H4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.97027 View
ENSG00000091831 ESR1 ENSG00000177733 HNRNPA0 H. sapiens SDL Slorth 0.970257 View
ENSG00000047410 TPR ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970214 View
ENSG00000091831 ESR1 ENSG00000111642 CHD4 H. sapiens SDL Slorth 0.970206 View
ENSG00000091831 ESR1 ENSG00000129152 MYOD1 H. sapiens SDL Slorth 0.970193 View
ENSG00000091831 ESR1 ENSG00000198793 MTOR H. sapiens SDL Slorth 0.970191 View
ENSG00000091831 ESR1 ENSG00000129691 ASH2L H. sapiens SDL Slorth 0.970183 View
ENSG00000091831 ESR1 ENSG00000170881 RNF139 H. sapiens SDL Slorth 0.970163 View
ENSG00000091831 ESR1 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.97016 View
ENSG00000071051 NCK2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970136 View
ENSG00000091831 ESR1 ENSG00000197299 BLM H. sapiens SDL Slorth 0.970116 View
ENSG00000072062 PRKACA ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.970114 View
ENSG00000091831 ESR1 ENSG00000137486 ARRB1 H. sapiens SDL Slorth 0.970114 View
ENSG00000091831 ESR1 ENSG00000095787 WAC H. sapiens SDL Slorth 0.970103 View
ENSG00000091831 ESR1 ENSG00000106976 DNM1 H. sapiens SDL Slorth 0.970103 View