XRN1

ENSG00000114127 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0003729 mRNA binding
GO:0003682 chromatin binding
GO:0004534 5'-3' exoribonuclease activity
GO:0003723 RNA binding
GO:0016787 hydrolase activity
GO:0004518 nuclease activity
GO:0003676 nucleic acid binding
GO:0008409 5'-3' exonuclease activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
XRN1 S. cerevisiae
xrn-1 C. elegans
pcm D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101266 CSNK2A1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.983319 View
ENSG00000114127 XRN1 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.982406 View
ENSG00000104365 IKBKB ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.981999 View
ENSG00000114127 XRN1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.980749 View
ENSG00000113558 SKP1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.979561 View
ENSG00000114127 XRN1 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.979262 View
ENSG00000005339 CREBBP ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.978748 View
ENSG00000114127 XRN1 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.978242 View
ENSG00000100644 HIF1A ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.978204 View
ENSG00000109670 FBXW7 ENSG00000114127 XRN1 H. sapiens SSL Slorth 0.977114 View
ENSG00000114127 XRN1 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.976023 View
ENSG00000114127 XRN1 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.97595 View
ENSG00000114127 XRN1 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.975742 View
ENSG00000114127 XRN1 ENSG00000197122 SRC H. sapiens SDL Slorth 0.975242 View
ENSG00000114127 XRN1 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.97522 View
ENSG00000110395 CBL ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.973428 View
ENSG00000114127 XRN1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.972633 View
ENSG00000091831 ESR1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.971882 View
ENSG00000114127 XRN1 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.970403 View
ENSG00000012048 BRCA1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.970296 View
ENSG00000103275 UBE2I ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.96924 View
ENSG00000109320 NFKB1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.969211 View
ENSG00000097007 ABL1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.969017 View
ENSG00000114127 XRN1 ENSG00000169083 AR H. sapiens SDL Slorth 0.968825 View
ENSG00000114127 XRN1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.968642 View
ENSG00000110092 CCND1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.967014 View
ENSG00000114127 XRN1 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.966866 View
ENSG00000100393 EP300 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.965782 View
ENSG00000114127 XRN1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.965164 View
ENSG00000055130 CUL1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.963768 View
ENSG00000100906 NFKBIA ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.963541 View
ENSG00000100030 MAPK1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.962823 View
ENSG00000082701 GSK3B ENSG00000114127 XRN1 H. sapiens SSL Slorth 0.962121 View
ENSG00000114127 XRN1 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.961863 View
ENSG00000109971 HSPA8 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.959163 View
ENSG00000114127 XRN1 ENSG00000140464 PML H. sapiens SDL Slorth 0.955405 View
ENSG00000112062 MAPK14 ENSG00000114127 XRN1 H. sapiens SSL Slorth 0.955319 View
ENSG00000110107 PRPF19 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.954311 View
ENSG00000080824 HSP90AA1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.95323 View
ENSG00000096384 HSP90AB1 ENSG00000114127 XRN1 H. sapiens SDL Slorth 0.952791 View