XRN1 - RB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XRN1	ENSG00000114127	No diseases in record	No drugs in record	DNA binding exonuclease activity protein binding mRNA binding chromatin binding 5'-3' exoribonuclease activity RNA binding hydrolase activity nuclease activity nucleic acid binding 5'-3' exonuclease activity	XRN1 (S. cerevisiae) xrn-1 (C. elegans) pcm (D. melanogaster)
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)