ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000101367 MAPRE1 H. sapiens SDL Slorth 0.966106 View
ENSG00000091831 ESR1 ENSG00000116489 CAPZA1 H. sapiens SDL Slorth 0.966099 View
ENSG00000091831 ESR1 ENSG00000144028 SNRNP200 H. sapiens SDL Slorth 0.966041 View
ENSG00000091831 ESR1 ENSG00000114423 CBLB H. sapiens SSL Slorth 0.965979 View
ENSG00000091831 ESR1 ENSG00000116350 SRSF4 H. sapiens SDL Slorth 0.965893 View
ENSG00000091831 ESR1 ENSG00000156304 SCAF4 H. sapiens SDL Slorth 0.965885 View
ENSG00000091831 ESR1 ENSG00000101310 SEC23B H. sapiens SDL Slorth 0.965864 View
ENSG00000075785 RAB7A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965777 View
ENSG00000058262 SEC61A1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965774 View
ENSG00000067606 PRKCZ ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965762 View
ENSG00000091831 ESR1 ENSG00000130177 CDC16 H. sapiens SDL Slorth 0.965727 View
ENSG00000055118 KCNH2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965727 View
ENSG00000016082 ISL1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965697 View
ENSG00000091831 ESR1 ENSG00000163904 SENP2 H. sapiens SDL Slorth 0.96569 View
ENSG00000069424 KCNAB2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965684 View
ENSG00000091831 ESR1 ENSG00000138069 RAB1A H. sapiens SDL Slorth 0.965619 View
ENSG00000091831 ESR1 ENSG00000166192 SENP8 H. sapiens SDL Slorth 0.965585 View
ENSG00000091831 ESR1 ENSG00000141543 EIF4A3 H. sapiens SDL Slorth 0.965585 View
ENSG00000091831 ESR1 ENSG00000118680 MYL12B H. sapiens SDL Slorth 0.965466 View
ENSG00000077549 CAPZB ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965465 View
ENSG00000070404 FSTL3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965413 View
ENSG00000019995 ZRANB1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965411 View
ENSG00000091831 ESR1 ENSG00000143549 TPM3 H. sapiens SDL Slorth 0.965342 View
ENSG00000091831 ESR1 ENSG00000125814 NAPB H. sapiens SDL Slorth 0.965322 View
ENSG00000091831 ESR1 ENSG00000188996 HUS1B H. sapiens SDL Slorth 0.965311 View
ENSG00000091831 ESR1 ENSG00000131828 PDHA1 H. sapiens SDL Slorth 0.965203 View
ENSG00000091831 ESR1 ENSG00000104313 EYA1 H. sapiens SDL Slorth 0.965152 View
ENSG00000091831 ESR1 ENSG00000139842 CUL4A H. sapiens SDL Slorth 0.965143 View
ENSG00000091831 ESR1 ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.965131 View
ENSG00000090539 CHRD ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965106 View
ENSG00000091831 ESR1 ENSG00000118689 FOXO3 H. sapiens SDL Slorth 0.965041 View
ENSG00000086598 TMED2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.965016 View
ENSG00000091831 ESR1 ENSG00000135018 UBQLN1 H. sapiens SDL Slorth 0.965013 View
ENSG00000091831 ESR1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.964988 View
ENSG00000091831 ESR1 ENSG00000143384 MCL1 H. sapiens SDL Slorth 0.964918 View
ENSG00000091831 ESR1 ENSG00000173039 RELA H. sapiens SDL Slorth 0.964901 View
ENSG00000091831 ESR1 ENSG00000167552 TUBA1A H. sapiens SDL Slorth 0.9649 View
ENSG00000091831 ESR1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.964884 View
ENSG00000091831 ESR1 ENSG00000143420 ENSA H. sapiens SDL Slorth 0.964863 View
ENSG00000091831 ESR1 ENSG00000146731 CCT6A H. sapiens SDL Slorth 0.964853 View