ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.964849 View
ENSG00000091831 ESR1 ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.964787 View
ENSG00000091831 ESR1 ENSG00000101752 MIB1 H. sapiens SDL Slorth 0.96474 View
ENSG00000091831 ESR1 ENSG00000101460 MAP1LC3A H. sapiens SDL Slorth 0.964732 View
ENSG00000091831 ESR1 ENSG00000148341 SH3GLB2 H. sapiens SDL Slorth 0.964724 View
ENSG00000091831 ESR1 ENSG00000136877 FPGS H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000161618 ALDH16A1 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000132681 ATP1A4 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000139370 SLC15A4 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000151846 PABPC3 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000120756 PLS1 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000111713 GYS2 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000183785 TUBA8 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000144909 OSBPL11 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000163017 ACTG2 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000138363 ATIC H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000143149 ALDH9A1 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000105357 MYH14 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000165801 ARHGEF40 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000145284 SCD5 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000113504 SLC12A7 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000197601 FAR1 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000139734 DIAPH3 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000132463 GRSF1 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000114374 USP9Y H. sapiens SDL Slorth 0.964675 View
ENSG00000091831 ESR1 ENSG00000125676 THOC2 H. sapiens SDL Slorth 0.964647 View
ENSG00000091831 ESR1 ENSG00000145495 MARCH6 H. sapiens SDL Slorth 0.964644 View
ENSG00000091831 ESR1 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.964621 View
ENSG00000091831 ESR1 ENSG00000141027 NCOR1 H. sapiens SDL Slorth 0.964596 View
ENSG00000091831 ESR1 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.964576 View
ENSG00000091831 ESR1 ENSG00000134333 LDHA H. sapiens SDL Slorth 0.964574 View
ENSG00000083093 PALB2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964569 View
ENSG00000091831 ESR1 ENSG00000159461 AMFR H. sapiens SDL Slorth 0.964516 View
ENSG00000067082 KLF6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964493 View
ENSG00000072518 MARK2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96444 View
ENSG00000076356 PLXNA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964386 View
ENSG00000085276 MECOM ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.964368 View
ENSG00000091831 ESR1 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.964358 View
ENSG00000091831 ESR1 ENSG00000255112 CHMP1B H. sapiens SDL Slorth 0.964355 View