ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000170385 SLC30A1 H. sapiens SDL Slorth 0.960247 View
ENSG00000091831 ESR1 ENSG00000149187 CELF1 H. sapiens SDL Slorth 0.960247 View
ENSG00000091831 ESR1 ENSG00000139163 ETNK1 H. sapiens SDL Slorth 0.960247 View
ENSG00000091831 ESR1 ENSG00000102879 CORO1A H. sapiens SDL Slorth 0.960247 View
ENSG00000091831 ESR1 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.960232 View
ENSG00000091831 ESR1 ENSG00000130726 TRIM28 H. sapiens SSL Slorth 0.960221 View
ENSG00000091831 ESR1 ENSG00000131459 GFPT2 H. sapiens SDL Slorth 0.960175 View
ENSG00000091831 ESR1 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.960131 View
ENSG00000091831 ESR1 ENSG00000104517 UBR5 H. sapiens SDL Slorth 0.960085 View
ENSG00000091831 ESR1 ENSG00000114166 KAT2B H. sapiens SDL Slorth 0.960068 View
ENSG00000091831 ESR1 ENSG00000127481 UBR4 H. sapiens SDL Slorth 0.959941 View
ENSG00000091831 ESR1 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.959929 View
ENSG00000091831 ESR1 ENSG00000164032 H2AFZ H. sapiens SDL Slorth 0.959914 View
ENSG00000091831 ESR1 ENSG00000095015 MAP3K1 H. sapiens SDL Slorth 0.959909 View
ENSG00000091831 ESR1 ENSG00000178573 MAF H. sapiens SDL Slorth 0.959899 View
ENSG00000082898 XPO1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.95989 View
ENSG00000091831 ESR1 ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.959889 View
ENSG00000091831 ESR1 ENSG00000100813 ACIN1 H. sapiens SDL Slorth 0.95983 View
ENSG00000091831 ESR1 ENSG00000154832 CXXC1 H. sapiens SDL Slorth 0.959805 View
ENSG00000091831 ESR1 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.959798 View
ENSG00000091831 ESR1 ENSG00000108953 YWHAE H. sapiens SDL Slorth 0.95978 View
ENSG00000079785 DDX1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959777 View
ENSG00000091831 ESR1 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.959775 View
ENSG00000091831 ESR1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.959702 View
ENSG00000091831 ESR1 ENSG00000116560 SFPQ H. sapiens SSL Slorth 0.959675 View
ENSG00000091831 ESR1 ENSG00000136068 FLNB H. sapiens SDL Slorth 0.95967 View
ENSG00000004700 RECQL ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959637 View
ENSG00000091831 ESR1 ENSG00000197153 HIST1H3J H. sapiens SDL Slorth 0.959629 View
ENSG00000091831 ESR1 ENSG00000186871 ERCC6L H. sapiens SDL Slorth 0.959601 View
ENSG00000091831 ESR1 ENSG00000129559 NEDD8 H. sapiens SDL Slorth 0.959585 View
ENSG00000091831 ESR1 ENSG00000166200 COPS2 H. sapiens SSL Slorth 0.959547 View
ENSG00000091831 ESR1 ENSG00000100934 SEC23A H. sapiens SDL Slorth 0.959538 View
ENSG00000075624 ACTB ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959435 View
ENSG00000091831 ESR1 ENSG00000198959 TGM2 H. sapiens SDL Slorth 0.959388 View
ENSG00000072310 SREBF1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959377 View
ENSG00000091831 ESR1 ENSG00000132694 ARHGEF11 H. sapiens SDL Slorth 0.959338 View
ENSG00000091831 ESR1 ENSG00000105173 CCNE1 H. sapiens SSL Slorth 0.959308 View
ENSG00000091831 ESR1 ENSG00000143632 ACTA1 H. sapiens SDL Slorth 0.959294 View
ENSG00000091831 ESR1 ENSG00000133101 CCNA1 H. sapiens SDL Slorth 0.959278 View
ENSG00000091831 ESR1 ENSG00000140464 PML H. sapiens SDL Slorth 0.959195 View