ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000138031 ADCY3 H. sapiens SDL Slorth 0.95917 View
ENSG00000036672 USP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959133 View
ENSG00000077782 FGFR1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959126 View
ENSG00000091831 ESR1 ENSG00000149925 ALDOA H. sapiens SDL Slorth 0.959109 View
ENSG00000091831 ESR1 ENSG00000111716 LDHB H. sapiens SDL Slorth 0.959109 View
ENSG00000091831 ESR1 ENSG00000107854 TNKS2 H. sapiens SDL Slorth 0.959093 View
ENSG00000091831 ESR1 ENSG00000136167 LCP1 H. sapiens SDL Slorth 0.959054 View
ENSG00000091831 ESR1 ENSG00000114416 FXR1 H. sapiens SDL Slorth 0.959054 View
ENSG00000091831 ESR1 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.959041 View
ENSG00000091831 ESR1 ENSG00000130522 JUND H. sapiens SSL Slorth 0.959024 View
ENSG00000091831 ESR1 ENSG00000111737 RAB35 H. sapiens SDL Slorth 0.958997 View
ENSG00000091831 ESR1 ENSG00000140416 TPM1 H. sapiens SDL Slorth 0.958993 View
ENSG00000091831 ESR1 ENSG00000198692 EIF1AY H. sapiens SDL Slorth 0.958981 View
ENSG00000091831 ESR1 ENSG00000124813 RUNX2 H. sapiens SDL Slorth 0.958854 View
ENSG00000091831 ESR1 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.958849 View
ENSG00000091831 ESR1 ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.958835 View
ENSG00000091831 ESR1 ENSG00000198947 DMD H. sapiens SDL Slorth 0.958834 View
ENSG00000065029 ZNF76 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958832 View
ENSG00000023445 BIRC3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958677 View
ENSG00000077092 RARB ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958665 View
ENSG00000091831 ESR1 ENSG00000170004 CHD3 H. sapiens SSL Slorth 0.958648 View
ENSG00000091831 ESR1 ENSG00000125733 TRIP10 H. sapiens SDL Slorth 0.958599 View
ENSG00000064655 EYA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958588 View
ENSG00000074201 CLNS1A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958562 View
ENSG00000091831 ESR1 ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.958549 View
ENSG00000091831 ESR1 ENSG00000122512 PMS2 H. sapiens SDL Slorth 0.958543 View
ENSG00000078403 MLLT10 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958525 View
ENSG00000091831 ESR1 ENSG00000155111 CDK19 H. sapiens SDL Slorth 0.958524 View
ENSG00000068366 ACSL4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958386 View
ENSG00000067048 DDX3Y ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958386 View
ENSG00000079215 SLC1A3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.958386 View
ENSG00000091831 ESR1 ENSG00000119414 PPP6C H. sapiens SDL Slorth 0.958296 View
ENSG00000091831 ESR1 ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.958288 View
ENSG00000091831 ESR1 ENSG00000128059 PPAT H. sapiens SDL Slorth 0.958288 View
ENSG00000091831 ESR1 ENSG00000171960 PPIH H. sapiens SSL Slorth 0.958228 View
ENSG00000091831 ESR1 ENSG00000165280 VCP H. sapiens SDL Slorth 0.958207 View
ENSG00000091831 ESR1 ENSG00000122367 LDB3 H. sapiens SDL Slorth 0.958203 View
ENSG00000091831 ESR1 ENSG00000103479 RBL2 H. sapiens SSL Slorth 0.958202 View
ENSG00000091831 ESR1 ENSG00000102755 FLT1 H. sapiens SDL Slorth 0.958201 View
ENSG00000091831 ESR1 ENSG00000131759 RARA H. sapiens SDL Slorth 0.958164 View