ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000134954 ETS1 H. sapiens SSL Slorth 0.955239 View
ENSG00000091831 ESR1 ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.955128 View
ENSG00000091831 ESR1 ENSG00000113758 DBN1 H. sapiens SDL Slorth 0.954997 View
ENSG00000066468 FGFR2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954914 View
ENSG00000091831 ESR1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.954724 View
ENSG00000008735 MAPK8IP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954713 View
ENSG00000091831 ESR1 ENSG00000104365 IKBKB H. sapiens SDL Slorth 0.954681 View
ENSG00000075886 TUBA3D ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000074370 ATP2A3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000068137 PLEKHH3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000082213 C5orf22 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000091136 LAMB1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000065833 ME1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000011052 NME1-NME2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000038532 CLEC16A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954622 View
ENSG00000091831 ESR1 ENSG00000205531 NAP1L4 H. sapiens SSL Slorth 0.954503 View
ENSG00000091831 ESR1 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.954459 View
ENSG00000091831 ESR1 ENSG00000157404 KIT H. sapiens SSL Slorth 0.954419 View
ENSG00000091831 ESR1 ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.954238 View
ENSG00000091831 ESR1 ENSG00000160211 G6PD H. sapiens SDL Slorth 0.954207 View
ENSG00000091831 ESR1 ENSG00000134982 APC H. sapiens SSL Slorth 0.95415 View
ENSG00000091039 OSBPL8 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954142 View
ENSG00000075415 SLC25A3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954142 View
ENSG00000072682 P4HA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954142 View
ENSG00000071626 DAZAP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.954142 View
ENSG00000091831 ESR1 ENSG00000160803 UBQLN4 H. sapiens SDL Slorth 0.95414 View
ENSG00000091831 ESR1 ENSG00000136527 TRA2B H. sapiens SSL Slorth 0.954127 View
ENSG00000091831 ESR1 ENSG00000154710 RABGEF1 H. sapiens SDL Slorth 0.954116 View
ENSG00000068654 POLR1A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.953984 View
ENSG00000091831 ESR1 ENSG00000185624 P4HB H. sapiens SDL Slorth 0.953956 View
ENSG00000091831 ESR1 ENSG00000109320 NFKB1 H. sapiens SSL Slorth 0.953733 View
ENSG00000091831 ESR1 ENSG00000111424 VDR H. sapiens SSL Slorth 0.953695 View
ENSG00000091831 ESR1 ENSG00000147316 MCPH1 H. sapiens SDL Slorth 0.953572 View
ENSG00000005007 UPF1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.95354 View
ENSG00000091831 ESR1 ENSG00000106462 EZH2 H. sapiens SSL Slorth 0.953485 View
ENSG00000091831 ESR1 ENSG00000120539 MASTL H. sapiens SDL Slorth 0.95347 View
ENSG00000091831 ESR1 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.953439 View
ENSG00000091831 ESR1 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.953436 View
ENSG00000007168 PAFAH1B1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.953369 View
ENSG00000091831 ESR1 ENSG00000105409 ATP1A3 H. sapiens SDL Slorth 0.953366 View