ESR1 - CYP3A4

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ESR1	ENSG00000091831	breast	BAZEDOXIFENE DIENESTROL DIETHYLSTILBESTROL DIETHYLSTILBESTROL DIPHOSPHATE ENCLOMIPHENE ESTRADIOL ESTRADIOL ACETATE ESTRADIOL CYPIONATE ESTRADIOL VALERATE ESTROGENS, CONJUGATED ESTROGENS, CONJUGATED SYNTHETIC A ESTROGENS, ESTERIFIED ESTRONE ESTRONE SULFURIC ACID ETHINYL ESTRADIOL FULVESTRANT MESTRANOL OSPEMIFENE POLYESTRADIOL PHOSPHATE QUINESTROL RALOXIFENE SYNTHETIC CONJUGATED ESTROGENS, B TAMOXIFEN TOREMIFENE	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity steroid binding protein binding beta-catenin binding transcription factor binding zinc ion binding enzyme binding nitric-oxide synthase regulator activity estrogen receptor activity estrogen response element binding RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding identical protein binding ATPase binding	No GO terms in record
CYP3A4	ENSG00000160868	No diseases in record	COBICISTAT	monooxygenase activity steroid binding iron ion binding steroid hydroxylase activity oxidoreductase activity oxygen binding enzyme binding heme binding vitamin D3 25-hydroxylase activity taurochenodeoxycholate 6alpha-hydroxylase activity caffeine oxidase activity albendazole monooxygenase activity quinine 3-monooxygenase activity testosterone 6-beta-hydroxylase activity aromatase activity vitamin D 24-hydroxylase activity estrogen 16-alpha-hydroxylase activity 1,8-cineole 2-exo-monooxygenase activity	Cyp6a9 (D. melanogaster) Cyp6a22 (D. melanogaster) Cyp6a21 (D. melanogaster) Cyp28d1 (D. melanogaster) Cyp28d2 (D. melanogaster)