FASN

ENSG00000169710 - H. sapiens

Pathways

Go term Description
GO:0004312 fatty acid synthase activity
GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0005515 protein binding
GO:0008144 drug binding
GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0031177 phosphopantetheine binding
GO:0042803 protein homodimerization activity
GO:0047117 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0070402 NADPH binding
GO:0098641 cadherin binding involved in cell-cell adhesion
GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity

Drugs

Drug name Description
ORLISTAT Fatty acid synthase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
CEM1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000012048 BRCA1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.987049 View
ENSG00000141510 TP53 ENSG00000169710 FASN H. sapiens SDL Slorth 0.981616 View
ENSG00000132646 PCNA ENSG00000169710 FASN H. sapiens SDL Slorth 0.981575 View
ENSG00000100393 EP300 ENSG00000169710 FASN H. sapiens SDL Slorth 0.981333 View
ENSG00000005339 CREBBP ENSG00000169710 FASN H. sapiens SDL Slorth 0.980928 View
ENSG00000162385 MAGOH ENSG00000169710 FASN H. sapiens SDL Slorth 0.980574 View
ENSG00000142208 AKT1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.98045 View
ENSG00000101266 CSNK2A1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.980209 View
ENSG00000123374 CDK2 ENSG00000169710 FASN H. sapiens SDL Slorth 0.980201 View
ENSG00000169083 AR ENSG00000169710 FASN H. sapiens SDL Slorth 0.979956 View
ENSG00000116478 HDAC1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.979028 View
ENSG00000136997 MYC ENSG00000169710 FASN H. sapiens SDL Slorth 0.978563 View
ENSG00000109670 FBXW7 ENSG00000169710 FASN H. sapiens SSL Slorth 0.97672 View
ENSG00000169710 FASN ENSG00000170315 UBB H. sapiens SDL Slorth 0.97663 View
ENSG00000100030 MAPK1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.97607 View
ENSG00000150991 UBC ENSG00000169710 FASN H. sapiens SDL Slorth 0.975742 View
ENSG00000168610 STAT3 ENSG00000169710 FASN H. sapiens SDL Slorth 0.974477 View
ENSG00000091831 ESR1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.973785 View
ENSG00000140464 PML ENSG00000169710 FASN H. sapiens SDL Slorth 0.973584 View
ENSG00000166949 SMAD3 ENSG00000169710 FASN H. sapiens SDL Slorth 0.972708 View
ENSG00000166167 BTRC ENSG00000169710 FASN H. sapiens SDL Slorth 0.970832 View
ENSG00000124762 CDKN1A ENSG00000169710 FASN H. sapiens SDL Slorth 0.969707 View
ENSG00000097007 ABL1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.969655 View
ENSG00000100644 HIF1A ENSG00000169710 FASN H. sapiens SDL Slorth 0.969641 View
ENSG00000133703 KRAS ENSG00000169710 FASN H. sapiens SSL Slorth 0.968825 View
ENSG00000110395 CBL ENSG00000169710 FASN H. sapiens SDL Slorth 0.968134 View
ENSG00000169710 FASN ENSG00000197122 SRC H. sapiens SDL Slorth 0.965401 View
ENSG00000146648 EGFR ENSG00000169710 FASN H. sapiens SDL Slorth 0.96428 View
ENSG00000168036 CTNNB1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.963992 View
ENSG00000139687 RB1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.96137 View
ENSG00000104365 IKBKB ENSG00000169710 FASN H. sapiens SDL Slorth 0.961058 View
ENSG00000103275 UBE2I ENSG00000169710 FASN H. sapiens SDL Slorth 0.958655 View
ENSG00000080824 HSP90AA1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.957272 View
ENSG00000113558 SKP1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.956943 View
ENSG00000169710 FASN ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.956311 View
ENSG00000096384 HSP90AB1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.956272 View
ENSG00000082701 GSK3B ENSG00000169710 FASN H. sapiens SSL Slorth 0.954832 View
ENSG00000169710 FASN ENSG00000177606 JUN H. sapiens SDL Slorth 0.954508 View
ENSG00000135486 HNRNPA1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.954109 View
ENSG00000100906 NFKBIA ENSG00000169710 FASN H. sapiens SDL Slorth 0.952972 View