FASN

ENSG00000169710 - H. sapiens

Pathways

Go term Description
GO:0004312 fatty acid synthase activity
GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0005515 protein binding
GO:0008144 drug binding
GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0031177 phosphopantetheine binding
GO:0042803 protein homodimerization activity
GO:0047117 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0070402 NADPH binding
GO:0098641 cadherin binding involved in cell-cell adhesion
GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity

Drugs

Drug name Description
ORLISTAT Fatty acid synthase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
CEM1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101146 RAE1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.952871 View
ENSG00000161057 PSMC2 ENSG00000169710 FASN H. sapiens SDL Slorth 0.952579 View
ENSG00000141646 SMAD4 ENSG00000169710 FASN H. sapiens SSL Slorth 0.951246 View
ENSG00000123374 CDK2 ENSG00000169710 FASN H. sapiens SSL Slorth 0.950299 View
ENSG00000103275 UBE2I ENSG00000169710 FASN H. sapiens SSL Slorth 0.949971 View
ENSG00000101266 CSNK2A1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.949605 View
ENSG00000097007 ABL1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.948932 View
ENSG00000109971 HSPA8 ENSG00000169710 FASN H. sapiens SDL Slorth 0.946489 View
ENSG00000160691 SHC1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.945442 View
ENSG00000055130 CUL1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.944916 View
ENSG00000132155 RAF1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.944565 View
ENSG00000168610 STAT3 ENSG00000169710 FASN H. sapiens SSL Slorth 0.944273 View
ENSG00000132155 RAF1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.94285 View
ENSG00000166949 SMAD3 ENSG00000169710 FASN H. sapiens SSL Slorth 0.941843 View
ENSG00000169375 SIN3A ENSG00000169710 FASN H. sapiens SDL Slorth 0.941137 View
ENSG00000109320 NFKB1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.940778 View
ENSG00000097046 CDC7 ENSG00000169710 FASN H. sapiens SSL Slorth 0.939295 View
ENSG00000169710 FASN ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.938793 View
ENSG00000112062 MAPK14 ENSG00000169710 FASN H. sapiens SSL Slorth 0.9383 View
ENSG00000113575 PPP2CA ENSG00000169710 FASN H. sapiens SSL Slorth 0.937432 View
ENSG00000169710 FASN ENSG00000185591 SP1 H. sapiens SDL Slorth 0.937185 View
ENSG00000169710 FASN ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.936896 View
ENSG00000169710 FASN ENSG00000173039 RELA H. sapiens SDL Slorth 0.936592 View
ENSG00000142541 RPL13A ENSG00000169710 FASN H. sapiens SDL Slorth 0.936446 View
ENSG00000142208 AKT1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.936177 View
ENSG00000136997 MYC ENSG00000169710 FASN H. sapiens SSL Slorth 0.935865 View
ENSG00000134086 VHL ENSG00000169710 FASN H. sapiens SSL Slorth 0.935732 View
ENSG00000100030 MAPK1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.934905 View
ENSG00000104365 IKBKB ENSG00000169710 FASN H. sapiens SSL Slorth 0.934288 View
ENSG00000072401 UBE2D1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.934236 View
ENSG00000149273 RPS3 ENSG00000169710 FASN H. sapiens SDL Slorth 0.933481 View
ENSG00000140464 PML ENSG00000169710 FASN H. sapiens SSL Slorth 0.933295 View
ENSG00000010810 FYN ENSG00000169710 FASN H. sapiens SSL Slorth 0.933114 View
ENSG00000137818 RPLP1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.932087 View
ENSG00000126067 PSMB2 ENSG00000169710 FASN H. sapiens SDL Slorth 0.930916 View
ENSG00000143799 PARP1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.930793 View
ENSG00000108443 RPS6KB1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.930428 View
ENSG00000169375 SIN3A ENSG00000169710 FASN H. sapiens SSL Slorth 0.930314 View
ENSG00000164924 YWHAZ ENSG00000169710 FASN H. sapiens SDL Slorth 0.927988 View
ENSG00000082701 GSK3B ENSG00000169710 FASN H. sapiens SDL Slorth 0.927776 View