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EGFR - FASN
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
EGFR
ENSG00000146648
glioma
NSCLC
AFATINIB
CETUXIMAB
ERLOTINIB
GEFITINIB
LAPATINIB
PANITUMUMAB
VANDETANIB
glycoprotein binding
chromatin binding
double-stranded DNA binding
MAP kinase kinase kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
epidermal growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
integrin binding
protein binding
calmodulin binding
ATP binding
enzyme binding
protein kinase binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
epidermal growth factor binding
actin filament binding
cadherin binding involved in cell-cell adhesion
nitric-oxide synthase regulator activity
protein domain specific binding
let-23 (C. elegans)
Egfr (D. melanogaster)
FASN
ENSG00000169710
No diseases in record
ORLISTAT
fatty acid synthase activity
[acyl-carrier-protein] S-acetyltransferase activity
[acyl-carrier-protein] S-malonyltransferase activity
3-oxoacyl-[acyl-carrier-protein] synthase activity
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
oleoyl-[acyl-carrier-protein] hydrolase activity
protein binding
drug binding
myristoyl-[acyl-carrier-protein] hydrolase activity
palmitoyl-[acyl-carrier-protein] hydrolase activity
phosphopantetheine binding
protein homodimerization activity
enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NADPH binding
cadherin binding involved in cell-cell adhesion
3-oxo-pimeloyl-[acp] methyl ester reductase activity
CEM1 (S. cerevisiae)