FLT4

ENSG00000037280 - H. sapiens

Pathways

Go term Description
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0019903 protein phosphatase binding

Drugs

Drug name Description
AXITINIB Vascular endothelial growth factor receptor inhibitor
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
soft tissue sarcoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000012048 BRCA1 ENSG00000037280 FLT4 H. sapiens SDL Slorth 0.991312 View
ENSG00000005339 CREBBP ENSG00000037280 FLT4 H. sapiens SDL Slorth 0.98787 View
ENSG00000037280 FLT4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.976874 View
ENSG00000037280 FLT4 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.976514 View
ENSG00000037280 FLT4 ENSG00000150991 UBC H. sapiens SDL Slorth 0.974107 View
ENSG00000037280 FLT4 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.973971 View
ENSG00000010810 FYN ENSG00000037280 FLT4 H. sapiens SDL Slorth 0.972614 View
ENSG00000037280 FLT4 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.971601 View
ENSG00000037280 FLT4 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.970997 View
ENSG00000037280 FLT4 ENSG00000110395 CBL H. sapiens SDL Slorth 0.969405 View
ENSG00000037280 FLT4 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.966959 View
ENSG00000037280 FLT4 ENSG00000197122 SRC H. sapiens SDL Slorth 0.966693 View
ENSG00000037280 FLT4 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.964682 View
ENSG00000037280 FLT4 ENSG00000164924 YWHAZ H. sapiens SDL Slorth 0.956611 View
ENSG00000037280 FLT4 ENSG00000158092 NCK1 H. sapiens SDL Slorth 0.952006 View
ENSG00000037280 FLT4 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.949124 View
ENSG00000037280 FLT4 ENSG00000169398 PTK2 H. sapiens SDL Slorth 0.947375 View
ENSG00000037280 FLT4 ENSG00000142192 APP H. sapiens SDL Slorth 0.946306 View
ENSG00000037280 FLT4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.945641 View
ENSG00000037280 FLT4 ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.943995 View
ENSG00000037280 FLT4 ENSG00000080824 HSP90AA1 H. sapiens SDL Slorth 0.94351 View
ENSG00000037280 FLT4 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.942825 View
ENSG00000037280 FLT4 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.942191 View
ENSG00000037280 FLT4 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.938426 View
ENSG00000010810 FYN ENSG00000037280 FLT4 H. sapiens SSL Slorth 0.935462 View
ENSG00000037280 FLT4 ENSG00000171105 INSR H. sapiens SDL Slorth 0.932049 View
ENSG00000037280 FLT4 ENSG00000165025 SYK H. sapiens SDL Slorth 0.931811 View
ENSG00000004700 RECQL ENSG00000037280 FLT4 H. sapiens SSL Slorth 0.930268 View
ENSG00000012048 BRCA1 ENSG00000037280 FLT4 H. sapiens SSL Slorth 0.927605 View
ENSG00000037280 FLT4 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.9274 View
ENSG00000037280 FLT4 ENSG00000124181 PLCG1 H. sapiens SDL Slorth 0.923103 View
ENSG00000037280 FLT4 ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.922792 View
ENSG00000037280 FLT4 ENSG00000096968 JAK2 H. sapiens SDL Slorth 0.920656 View
ENSG00000037280 FLT4 ENSG00000111276 CDKN1B H. sapiens SDL Slorth 0.917935 View
ENSG00000005339 CREBBP ENSG00000037280 FLT4 H. sapiens SSL Slorth 0.910258 View
ENSG00000037280 FLT4 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.909027 View
ENSG00000037280 FLT4 ENSG00000128052 KDR H. sapiens SDL Slorth 0.903975 View
ENSG00000037280 FLT4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.900597 View
ENSG00000037280 FLT4 ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.823464 View
ENSG00000004897 CDC27 ENSG00000037280 FLT4 H. sapiens SSL Slorth 0.820277 View