JAK3

ENSG00000105639 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding

Drugs

Drug name Description
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
acute megakaryocytic leukaemia
ETP ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000012124 CD22 ENSG00000105639 JAK3 H. sapiens SSL BioGRID 1.0 View
ENSG00000105639 JAK3 ENSG00000105835 NAMPT H. sapiens SSL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.98443 View
ENSG00000005339 CREBBP ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.979511 View
ENSG00000091831 ESR1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.978812 View
ENSG00000100030 MAPK1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.977948 View
ENSG00000105639 JAK3 ENSG00000150991 UBC H. sapiens SDL Slorth 0.976396 View
ENSG00000105639 JAK3 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.973323 View
ENSG00000105639 JAK3 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.972376 View
ENSG00000080824 HSP90AA1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.969628 View
ENSG00000105639 JAK3 ENSG00000197122 SRC H. sapiens SDL Slorth 0.968002 View
ENSG00000105639 JAK3 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.967095 View
ENSG00000012048 BRCA1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.966633 View
ENSG00000105639 JAK3 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.965944 View
ENSG00000097007 ABL1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.965383 View
ENSG00000105639 JAK3 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.961756 View
ENSG00000100644 HIF1A ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.956947 View
ENSG00000096968 JAK2 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.956084 View
ENSG00000105639 JAK3 ENSG00000169083 AR H. sapiens SDL Slorth 0.953931 View
ENSG00000105639 JAK3 ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.953002 View
ENSG00000105639 JAK3 ENSG00000110395 CBL H. sapiens SDL Slorth 0.951538 View
ENSG00000105639 JAK3 ENSG00000173039 RELA H. sapiens SDL Slorth 0.949775 View
ENSG00000105639 JAK3 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.949281 View
ENSG00000105639 JAK3 ENSG00000169398 PTK2 H. sapiens SDL Slorth 0.947534 View
ENSG00000105639 JAK3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.946604 View
ENSG00000097046 CDC7 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.942743 View
ENSG00000097007 ABL1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.937581 View
ENSG00000105639 JAK3 ENSG00000109670 FBXW7 H. sapiens SSL Slorth 0.93478 View
ENSG00000101146 RAE1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.933947 View
ENSG00000100030 MAPK1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.933389 View
ENSG00000105639 JAK3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.933068 View
ENSG00000101336 HCK ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.930079 View
ENSG00000105639 JAK3 ENSG00000171720 HDAC3 H. sapiens SDL Slorth 0.929627 View
ENSG00000010810 FYN ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.927795 View
ENSG00000105639 JAK3 ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.922429 View
ENSG00000004700 RECQL ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.921502 View
ENSG00000084676 NCOA1 ENSG00000105639 JAK3 H. sapiens SDL Slorth 0.920854 View
ENSG00000105639 JAK3 ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.920635 View
ENSG00000105639 JAK3 ENSG00000107643 MAPK8 H. sapiens SDL Slorth 0.916558 View
ENSG00000101266 CSNK2A1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.914689 View