JAK3

ENSG00000105639 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding

Drugs

Drug name Description
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
acute megakaryocytic leukaemia
ETP ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070010 UFD1L ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.855981 View
ENSG00000105639 JAK3 ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.854878 View
ENSG00000105639 JAK3 ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.854266 View
ENSG00000105639 JAK3 ENSG00000170345 FOS H. sapiens SSL Slorth 0.853334 View
ENSG00000005339 CREBBP ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.852842 View
ENSG00000105639 JAK3 ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.85017 View
ENSG00000067560 RHOA ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.850066 View
ENSG00000105639 JAK3 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.849319 View
ENSG00000072401 UBE2D1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.849208 View
ENSG00000105639 JAK3 ENSG00000108443 RPS6KB1 H. sapiens SSL Slorth 0.848784 View
ENSG00000062822 POLD1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.846293 View
ENSG00000082701 GSK3B ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.845608 View
ENSG00000105639 JAK3 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.842759 View
ENSG00000105639 JAK3 ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.839876 View
ENSG00000105639 JAK3 ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.839756 View
ENSG00000105639 JAK3 ENSG00000108953 YWHAE H. sapiens SSL Slorth 0.83855 View
ENSG00000105639 JAK3 ENSG00000141564 RPTOR H. sapiens SSL Slorth 0.838174 View
ENSG00000105639 JAK3 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.837857 View
ENSG00000102882 MAPK3 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.836352 View
ENSG00000105639 JAK3 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.835979 View
ENSG00000105639 JAK3 ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.835414 View
ENSG00000105639 JAK3 ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.831742 View
ENSG00000091831 ESR1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.83061 View
ENSG00000096968 JAK2 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.829252 View
ENSG00000105639 JAK3 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.826501 View
ENSG00000105639 JAK3 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.824928 View
ENSG00000105639 JAK3 ENSG00000116044 NFE2L2 H. sapiens SSL Slorth 0.824489 View
ENSG00000105639 JAK3 ENSG00000141367 CLTC H. sapiens SSL Slorth 0.821334 View
ENSG00000105639 JAK3 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.820881 View
ENSG00000105639 JAK3 ENSG00000126261 UBA2 H. sapiens SSL Slorth 0.820093 View
ENSG00000105639 JAK3 ENSG00000151247 EIF4E H. sapiens SSL Slorth 0.819755 View
ENSG00000105639 JAK3 ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.817875 View
ENSG00000105639 JAK3 ENSG00000115904 SOS1 H. sapiens SSL Slorth 0.816205 View
ENSG00000105639 JAK3 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.814902 View
ENSG00000105639 JAK3 ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.813493 View
ENSG00000105639 JAK3 ENSG00000132341 RAN H. sapiens SSL Slorth 0.81328 View
ENSG00000105639 JAK3 ENSG00000124486 USP9X H. sapiens SSL Slorth 0.810377 View
ENSG00000105639 JAK3 ENSG00000121774 KHDRBS1 H. sapiens SSL Slorth 0.810044 View
ENSG00000105639 JAK3 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.806516 View
ENSG00000105639 JAK3 ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.806095 View