|
Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
|
JAK3
|
ENSG00000105639
|
acute megakaryocytic leukaemia
ETP ALL
|
TOFACITINIB
|
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
protein binding
ATP binding
protein phosphatase binding
|
hop (D. melanogaster)
|
|
PTPN11
|
ENSG00000179295
|
JMML
AML
MDS
|
No drugs in record
|
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
cell adhesion molecule binding
peptide hormone receptor binding
|
PTP1 (S. cerevisiae)
ptp-2 (C. elegans)
csw (D. melanogaster)
|
