FLT3

ENSG00000122025 - H. sapiens

Pathways

Go term Description
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004896 cytokine receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0032403 protein complex binding
GO:0035259 glucocorticoid receptor binding
GO:0042803 protein homodimerization activity

Drugs

Drug name Description
CABOZANTINIB
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
AML
ALL

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000122025 FLT3 ENSG00000134086 VHL H. sapiens SSL BioGRID 1.0 View
ENSG00000012048 BRCA1 ENSG00000122025 FLT3 H. sapiens SSL BioGRID 1.0 View
ENSG00000122025 FLT3 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.984925 View
ENSG00000122025 FLT3 ENSG00000136997 MYC H. sapiens SDL Slorth 0.983049 View
ENSG00000012048 BRCA1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.982977 View
ENSG00000122025 FLT3 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.981916 View
ENSG00000110395 CBL ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.981502 View
ENSG00000122025 FLT3 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.981122 View
ENSG00000109670 FBXW7 ENSG00000122025 FLT3 H. sapiens SSL Slorth 0.981076 View
ENSG00000100393 EP300 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.98091 View
ENSG00000091831 ESR1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.980738 View
ENSG00000005339 CREBBP ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.980412 View
ENSG00000116478 HDAC1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.979683 View
ENSG00000122025 FLT3 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.979508 View
ENSG00000122025 FLT3 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.979354 View
ENSG00000122025 FLT3 ENSG00000170315 UBB H. sapiens SDL Slorth 0.978697 View
ENSG00000122025 FLT3 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.97831 View
ENSG00000122025 FLT3 ENSG00000177606 JUN H. sapiens SDL Slorth 0.978263 View
ENSG00000122025 FLT3 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.976904 View
ENSG00000122025 FLT3 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.974365 View
ENSG00000122025 FLT3 ENSG00000169083 AR H. sapiens SDL Slorth 0.974158 View
ENSG00000122025 FLT3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.973935 View
ENSG00000100030 MAPK1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.973823 View
ENSG00000122025 FLT3 ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.973562 View
ENSG00000122025 FLT3 ENSG00000150991 UBC H. sapiens SDL Slorth 0.97354 View
ENSG00000101266 CSNK2A1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.973501 View
ENSG00000100906 NFKBIA ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.972898 View
ENSG00000122025 FLT3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.972823 View
ENSG00000122025 FLT3 ENSG00000164924 YWHAZ H. sapiens SDL Slorth 0.972704 View
ENSG00000122025 FLT3 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.972219 View
ENSG00000122025 FLT3 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.971746 View
ENSG00000122025 FLT3 ENSG00000197122 SRC H. sapiens SDL Slorth 0.971712 View
ENSG00000122025 FLT3 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.971452 View
ENSG00000097007 ABL1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.970193 View
ENSG00000122025 FLT3 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.970093 View
ENSG00000100644 HIF1A ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.969491 View
ENSG00000122025 FLT3 ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.969254 View
ENSG00000113558 SKP1 ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.969013 View
ENSG00000122025 FLT3 ENSG00000173039 RELA H. sapiens SDL Slorth 0.968457 View
ENSG00000082701 GSK3B ENSG00000122025 FLT3 H. sapiens SDL Slorth 0.968262 View