FLT3 - RB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FLT3	ENSG00000122025	AML ALL	CABOZANTINIB SORAFENIB SUNITINIB	transmembrane receptor protein tyrosine kinase activity cytokine receptor activity vascular endothelial growth factor-activated receptor activity protein binding ATP binding protein complex binding glucocorticoid receptor binding protein homodimerization activity	Pvr (D. melanogaster)
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)