HMGCR

ENSG00000113161 - H. sapiens

Pathways

Go term Description
GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0005515 protein binding
GO:0042282 hydroxymethylglutaryl-CoA reductase activity
GO:0042803 protein homodimerization activity
GO:0050662 coenzyme binding
GO:0051721 protein phosphatase 2A binding
GO:0070402 NADPH binding
GO:0050661 NADP binding

Drugs

Drug name Description
ATORVASTATIN HMG-CoA reductase inhibitor
CERIVASTATIN HMG-CoA reductase inhibitor
FLUVASTATIN HMG-CoA reductase inhibitor
LOVASTATIN HMG-CoA reductase inhibitor
PITAVASTATIN HMG-CoA reductase inhibitor
PRAVASTATIN HMG-CoA reductase inhibitor
ROSUVASTATIN HMG-CoA reductase inhibitor
SIMVASTATIN HMG-CoA reductase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
HMG1 S. cerevisiae
HMG2 S. cerevisiae
Hmgcr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113161 HMGCR ENSG00000128311 TST H. sapiens SSL BioGRID 1.0 View
ENSG00000139842 CUL4A ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000159217 IGF2BP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000088247 KHSRP H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000115275 MOGS H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000103148 NPRL3 H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000158571 PFKFB1 H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000132356 PRKAA1 H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000138069 RAB1A H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000174903 RAB1B H. sapiens SSL BioGRID 1.0 View
ENSG00000105221 AKT2 ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000154710 RABGEF1 H. sapiens SSL BioGRID 1.0 View
ENSG00000148218 ALAD ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000101310 SEC23B H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000071564 TCF3 H. sapiens SSL BioGRID 1.0 View
ENSG00000149182 ARFGAP2 ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000177479 ARIH2 ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000274891 TRAPPC12 H. sapiens SSL BioGRID 1.0 View
ENSG00000104472 CHRAC1 ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000113597 TRAPPC13 H. sapiens SSL BioGRID 1.0 View
ENSG00000159692 CTBP1 ENSG00000113161 HMGCR H. sapiens SSL BioGRID 1.0 View
ENSG00000113161 HMGCR ENSG00000132646 PCNA H. sapiens SDL Slorth 0.984078 View
ENSG00000113161 HMGCR ENSG00000136997 MYC H. sapiens SDL Slorth 0.982666 View
ENSG00000113161 HMGCR ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.981492 View
ENSG00000091831 ESR1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.980381 View
ENSG00000109670 FBXW7 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.979005 View
ENSG00000113161 HMGCR ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.977972 View
ENSG00000113161 HMGCR ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.977693 View
ENSG00000113161 HMGCR ENSG00000133703 KRAS H. sapiens SSL Slorth 0.97759 View
ENSG00000113161 HMGCR ENSG00000169083 AR H. sapiens SDL Slorth 0.977493 View
ENSG00000113161 HMGCR ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.977253 View
ENSG00000113161 HMGCR ENSG00000177606 JUN H. sapiens SDL Slorth 0.975534 View
ENSG00000113161 HMGCR ENSG00000139687 RB1 H. sapiens SDL Slorth 0.975468 View
ENSG00000113161 HMGCR ENSG00000197122 SRC H. sapiens SDL Slorth 0.975347 View
ENSG00000113161 HMGCR ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.975084 View
ENSG00000113161 HMGCR ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.975024 View
ENSG00000113161 HMGCR ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.974501 View
ENSG00000113161 HMGCR ENSG00000146648 EGFR H. sapiens SDL Slorth 0.974259 View
ENSG00000113161 HMGCR ENSG00000185591 SP1 H. sapiens SDL Slorth 0.973947 View