HMGCR

ENSG00000113161 - H. sapiens

Pathways

Go term Description
GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0005515 protein binding
GO:0042282 hydroxymethylglutaryl-CoA reductase activity
GO:0042803 protein homodimerization activity
GO:0050662 coenzyme binding
GO:0051721 protein phosphatase 2A binding
GO:0070402 NADPH binding
GO:0050661 NADP binding

Drugs

Drug name Description
ATORVASTATIN HMG-CoA reductase inhibitor
CERIVASTATIN HMG-CoA reductase inhibitor
FLUVASTATIN HMG-CoA reductase inhibitor
LOVASTATIN HMG-CoA reductase inhibitor
PITAVASTATIN HMG-CoA reductase inhibitor
PRAVASTATIN HMG-CoA reductase inhibitor
ROSUVASTATIN HMG-CoA reductase inhibitor
SIMVASTATIN HMG-CoA reductase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
HMG1 S. cerevisiae
HMG2 S. cerevisiae
Hmgcr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000105974 CAV1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.901792 View
ENSG00000113161 HMGCR ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.886252 View
ENSG00000110713 NUP98 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.881605 View
ENSG00000113161 HMGCR ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.874813 View
ENSG00000080815 PSEN1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.866841 View
ENSG00000078140 UBE2K ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.862969 View
ENSG00000049759 NEDD4L ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.855872 View
ENSG00000105810 CDK6 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.839529 View
ENSG00000075624 ACTB ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.82137 View
ENSG00000091831 ESR1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.815347 View
ENSG00000113161 HMGCR ENSG00000176105 YES1 H. sapiens SSL Slorth 0.79909 View
ENSG00000110092 CCND1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.798994 View
ENSG00000012048 BRCA1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.797727 View
ENSG00000093009 CDC45 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.783323 View
ENSG00000096717 SIRT1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.764901 View
ENSG00000113161 HMGCR ENSG00000127022 CANX H. sapiens SSL Slorth 0.756881 View