HMGCR

ENSG00000113161 - H. sapiens

Pathways

Go term Description
GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0005515 protein binding
GO:0042282 hydroxymethylglutaryl-CoA reductase activity
GO:0042803 protein homodimerization activity
GO:0050662 coenzyme binding
GO:0051721 protein phosphatase 2A binding
GO:0070402 NADPH binding
GO:0050661 NADP binding

Drugs

Drug name Description
ATORVASTATIN HMG-CoA reductase inhibitor
CERIVASTATIN HMG-CoA reductase inhibitor
FLUVASTATIN HMG-CoA reductase inhibitor
LOVASTATIN HMG-CoA reductase inhibitor
PITAVASTATIN HMG-CoA reductase inhibitor
PRAVASTATIN HMG-CoA reductase inhibitor
ROSUVASTATIN HMG-CoA reductase inhibitor
SIMVASTATIN HMG-CoA reductase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
HMG1 S. cerevisiae
HMG2 S. cerevisiae
Hmgcr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113161 HMGCR ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.973733 View
ENSG00000113161 HMGCR ENSG00000141510 TP53 H. sapiens SDL Slorth 0.971636 View
ENSG00000113161 HMGCR ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.970909 View
ENSG00000113161 HMGCR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.97017 View
ENSG00000113161 HMGCR ENSG00000170315 UBB H. sapiens SDL Slorth 0.970123 View
ENSG00000097007 ABL1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.969452 View
ENSG00000113161 HMGCR ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.968923 View
ENSG00000113161 HMGCR ENSG00000173039 RELA H. sapiens SDL Slorth 0.968505 View
ENSG00000113161 HMGCR ENSG00000164924 YWHAZ H. sapiens SDL Slorth 0.968392 View
ENSG00000100393 EP300 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.968372 View
ENSG00000113161 HMGCR ENSG00000150991 UBC H. sapiens SDL Slorth 0.967273 View
ENSG00000110395 CBL ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.967262 View
ENSG00000012048 BRCA1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.967079 View
ENSG00000100644 HIF1A ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.966466 View
ENSG00000101266 CSNK2A1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.965043 View
ENSG00000005339 CREBBP ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.964934 View
ENSG00000100030 MAPK1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.964023 View
ENSG00000103275 UBE2I ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.963958 View
ENSG00000101146 RAE1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.963441 View
ENSG00000110092 CCND1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.96292 View
ENSG00000113161 HMGCR ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.961338 View
ENSG00000113161 HMGCR ENSG00000113558 SKP1 H. sapiens SDL Slorth 0.952721 View
ENSG00000097046 CDC7 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.949295 View
ENSG00000113161 HMGCR ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.949285 View
ENSG00000080824 HSP90AA1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.945854 View
ENSG00000082701 GSK3B ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.944594 View
ENSG00000096384 HSP90AB1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.938888 View
ENSG00000109971 HSPA8 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.936068 View
ENSG00000055130 CUL1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.93385 View
ENSG00000101868 POLA1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.933306 View
ENSG00000004700 RECQL ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.930875 View
ENSG00000100906 NFKBIA ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.928909 View
ENSG00000113161 HMGCR ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.923995 View
ENSG00000108443 RPS6KB1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.913201 View
ENSG00000110107 PRPF19 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.91295 View
ENSG00000070010 UFD1L ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.912938 View
ENSG00000113161 HMGCR ENSG00000166167 BTRC H. sapiens SDL Slorth 0.911229 View
ENSG00000104365 IKBKB ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.909634 View
ENSG00000109320 NFKB1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.906784 View
ENSG00000062822 POLD1 ENSG00000113161 HMGCR H. sapiens SSL Slorth 0.903104 View