HMGCR - AKT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HMGCR	ENSG00000113161	No diseases in record	ATORVASTATIN CERIVASTATIN FLUVASTATIN LOVASTATIN PITAVASTATIN PRAVASTATIN ROSUVASTATIN SIMVASTATIN	hydroxymethylglutaryl-CoA reductase (NADPH) activity protein binding hydroxymethylglutaryl-CoA reductase activity protein homodimerization activity coenzyme binding protein phosphatase 2A binding NADPH binding NADP binding	HMG1 (S. cerevisiae) HMG2 (S. cerevisiae) Hmgcr (D. melanogaster)
AKT1	ENSG00000142208	breast colorectal ovarian NSCLC	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein kinase C binding protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding kinase activity enzyme binding nitric-oxide synthase regulator activity GTPase activating protein binding identical protein binding phosphatidylinositol-3,4-bisphosphate binding protein phosphatase 2A binding 14-3-3 protein binding phosphatidylinositol binding	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) akt-1 (C. elegans) akt-2 (C. elegans) Akt1 (D. melanogaster)