HMGCR - MYC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HMGCR	ENSG00000113161	No diseases in record	ATORVASTATIN CERIVASTATIN FLUVASTATIN LOVASTATIN PITAVASTATIN PRAVASTATIN ROSUVASTATIN SIMVASTATIN	hydroxymethylglutaryl-CoA reductase (NADPH) activity protein binding hydroxymethylglutaryl-CoA reductase activity protein homodimerization activity coenzyme binding protein phosphatase 2A binding NADPH binding NADP binding	HMG1 (S. cerevisiae) HMG2 (S. cerevisiae) Hmgcr (D. melanogaster)
MYC	ENSG00000136997	Burkitt lymphoma amplified in other cancers B-CLL	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein complex binding protein dimerization activity repressing transcription factor binding E-box binding	No GO terms in record