HMGCR - SRC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HMGCR	ENSG00000113161	No diseases in record	ATORVASTATIN CERIVASTATIN FLUVASTATIN LOVASTATIN PITAVASTATIN PRAVASTATIN ROSUVASTATIN SIMVASTATIN	hydroxymethylglutaryl-CoA reductase (NADPH) activity protein binding hydroxymethylglutaryl-CoA reductase activity protein homodimerization activity coenzyme binding protein phosphatase 2A binding NADPH binding NADP binding	HMG1 (S. cerevisiae) HMG2 (S. cerevisiae) Hmgcr (D. melanogaster)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)