SIRT1 - VDR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
VDR	ENSG00000111424	No diseases in record	CALCIFEDIOL CALCIPOTRIENE CALCITRIOL CHOLECALCIFEROL DOXERCALCIFEROL ERGOCALCIFEROL PARICALCITOL	DNA binding steroid hormone receptor activity protein binding zinc ion binding calcitriol receptor activity lithocholic acid receptor activity sequence-specific DNA binding retinoid X receptor binding calcitriol binding lithocholic acid binding transcription factor activity, sequence-specific DNA binding vitamin D response element binding	EcR (D. melanogaster)